CRACR2A and FAM156A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CRACR2A	FAM156A
Description		calcium release activated channel regulator 2A	family with sequence similarity 156 member A
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Immunological Synapse Extracellular Region Cytoplasm Golgi Apparatus Microtubule Organizing Center Cytoskeleton Plasma Membrane Membrane Vesicle Trans-Golgi Network Membrane Weibel-Palade Body Specific Granule Lumen Specific Granule	Nuclear Envelope Membrane
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Calcium Ion Binding Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding	Protein Binding
	Biological Process	Store-operated Calcium Entry Adaptive Immune Response Immune System Process Monoatomic Ion Transport Calcium Ion Transport Intracellular Protein Localization Vesicle-mediated Transport Endosomal Transport Activation Of Store-operated Calcium Channel Activity Response To Histamine T-helper 1 Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Calcium Ion Transport
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Severe insulin-deficient type 2 diabetes ( 34737425)
Interacting Genes		35 interacting genes: ANKRD29 ASB3 ATN1 CCHCR1 CDC23 DDIT3 FAM156A FAM156B FAM86C1P FKBP6 GIGYF1 GOLGA2 KRT31 KRT75 KRTAP13-1 KRTAP19-5 LRIF1 MDFI MID2 MKRN3 NOTCH2NLA OIP5 PNMA5 POLR1C RBAK RORB SLAIN1 SORBS3 TLE5 TRAF1 TRIM29 USP2 ZC2HC1C ZNF20 ZNF655	7 interacting genes: ATRIP CRACR2A GADD45G MAGEA11 SAT1 TEX11 TFIP11
Entrez ID		84766	29057
HPRD ID		10079	06683
Ensembl ID		ENSG00000130038	ENSG00000268350
Uniprot IDs		Q9BSW2	Q8NDB6
PDB IDs		6PSD
Enriched GO Terms of Interacting Partners?		Identical Protein Binding	Spermidine Acetylation Putrescine Catabolic Process Spermidine Binding Positive Regulation Of JNK Cascade Spliceosomal Complex Disassembly Gene Conversion Meiotic Gene Conversion ATR-ATRIP Complex Diamine N-acetyltransferase Activity U2-type Post-mRNA Release Spliceosomal Complex Male Meiosis Chromosome Segregation Polyamine Catabolic Process Regulation Of JNK Cascade Regulation Of Double-strand Break Repair DNA Metabolic Process Chiasma Assembly Activation Of Store-operated Calcium Channel Activity Positive Regulation Of Store-operated Calcium Channel Activity Weibel-Palade Body Spermidine Metabolic Process Putrescine Metabolic Process Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Protection From Non-homologous End Joining At Telomere Central Element Regulation Of DNA Repair Store-operated Calcium Entry Response To Histamine
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