CRACR2A and FAM156B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CRACR2A	FAM156B
Description		calcium release activated channel regulator 2A	family with sequence similarity 156 member B
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Immunological Synapse Extracellular Region Cytoplasm Golgi Apparatus Microtubule Organizing Center Cytoskeleton Plasma Membrane Membrane Vesicle Trans-Golgi Network Membrane Weibel-Palade Body Specific Granule Lumen Specific Granule	Nuclear Envelope Membrane
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Calcium Ion Binding Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding	Protein Binding
	Biological Process	Store-operated Calcium Entry Adaptive Immune Response Immune System Process Monoatomic Ion Transport Calcium Ion Transport Intracellular Protein Localization Vesicle-mediated Transport Endosomal Transport Activation Of Store-operated Calcium Channel Activity Response To Histamine T-helper 1 Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Calcium Ion Transport
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Severe insulin-deficient type 2 diabetes ( 34737425)
Interacting Genes		35 interacting genes: ANKRD29 ASB3 ATN1 CCHCR1 CDC23 DDIT3 FAM156A FAM156B FAM86C1P FKBP6 GIGYF1 GOLGA2 KRT31 KRT75 KRTAP13-1 KRTAP19-5 LRIF1 MDFI MID2 MKRN3 NOTCH2NLA OIP5 PNMA5 POLR1C RBAK RORB SLAIN1 SORBS3 TLE5 TRAF1 TRIM29 USP2 ZC2HC1C ZNF20 ZNF655	2 interacting genes: CRACR2A GADD45G
Entrez ID		84766	727866
HPRD ID		10079
Ensembl ID		ENSG00000130038	ENSG00000179304
Uniprot IDs		Q9BSW2	Q8NDB6
PDB IDs		6PSD
Enriched GO Terms of Interacting Partners?		Identical Protein Binding	Positive Regulation Of JNK Cascade Regulation Of JNK Cascade Positive Regulation Of MAPK Cascade Activation Of Store-operated Calcium Channel Activity Positive Regulation Of Store-operated Calcium Channel Activity Weibel-Palade Body Store-operated Calcium Entry Response To Histamine Regulation Of MAPK Cascade Specific Granule T-helper 1 Cell Differentiation Positive Regulation Of Cation Channel Activity Positive Regulation Of P38MAPK Cascade Positive Regulation Of Intracellular Signal Transduction Regulation Of P38MAPK Cascade T Cell Differentiation Involved In Immune Response Positive Regulation Of Ion Transmembrane Transporter Activity T-helper Cell Differentiation Immunological Synapse Positive Regulation Of Transporter Activity CD4-positive, Alpha-beta T Cell Differentiation Specific Granule Lumen CD4-positive, Alpha-beta T Cell Activation Positive Regulation Of Signal Transduction T Cell Activation Involved In Immune Response Alpha-beta T Cell Differentiation G Protein Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Cold-induced Thermogenesis Microtubule Organizing Center Regulation Of Transmembrane Transporter Activity Alpha-beta T Cell Activation Positive Regulation Of Calcium Ion Transport Regulation Of Monoatomic Ion Transmembrane Transporter Activity Trans-Golgi Network Membrane Regulation Of Intracellular Signal Transduction Positive Regulation Of Cation Transmembrane Transport Lymphocyte Activation Involved In Immune Response Positive Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Cold-induced Thermogenesis Leukocyte Activation Involved In Immune Response T Cell Differentiation Cell Activation Involved In Immune Response Cell Differentiation
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