ANKRA2 and TSHZ3

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		ANKRA2	TSHZ3
Name		ankyrin repeat family A member 2	teashirt zinc finger homeobox 3
Structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton Membrane Protein-containing Complex 3M Complex	Chromatin Nucleus Nucleoplasm Plasma Membrane Growth Cone Cell Projection
	Molecular Function	Protein Binding Protein Kinase Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding Low-density Lipoprotein Particle Receptor Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Gene Expression Regulation Of Protein-containing Complex Assembly	Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Positive Regulation Of Synaptic Transmission, Glutamatergic Long-term Synaptic Potentiation
GWAS		Monobrow thickness ( 26926045 )	Adventurousness ( 30643258 ) Chronotype ( 30696823 ) Cognitive performance ( 19734545 ) Corneal astigmatism ( 30306274 ) Diastolic blood pressure ( 27841878 ) Falling risk ( 32999390 ) FEV1 ( 30804560 ) Fractional exhaled nitric oxide (childhood) ( 24315451 ) General risk tolerance (MTAG) ( 30643258 ) Lung function (FEV1/FVC) ( 30061609 30804560 ) Peak expiratory flow ( 30804560 ) Photic sneeze reflex ( 27182965 ) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377 ) Post bronchodilator FEV1 in COPD ( 26634245 ) Refractive error ( 32231278 ) Systemising ( 31508503 ) Systolic blood pressure ( 27841878 ) Vertical cup-disc ratio (multi-trait analysis) ( 31959993 )
Interacting Genes		13 interacting genes: ABL1 APP CDKN2A HDAC4 HDAC5 HDAC9 LRP2 MPL NEK6 PDE3B RFX7 SAMD4A TSHZ3	30 interacting genes: ANKRA2 APBB1 APEX2 CCHCR1 CEP63 CEP70 COG6 CTBP1 CTBP2 GOLGA2 HSF2BP KASH5 KRT31 KRT40 LRRC73 MAD1L1 MRPL28 MTUS2 PIBF1 RINT1 ROPN1 SPAG5 TAX1BP1 TEPSIN TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TSC1
Entrez ID		57763	57616
HPRD ID		12044	18351
Ensembl ID		ENSG00000164331	ENSG00000121297
Uniprot IDs		Q9H9E1	Q63HK5
PDB IDs		3SO8 3V2O 3V2X 3V31 4LG6 4QQI 8CXG 8CXH 8CXI	2DMI
GO Terms Enriched among Interactors		Histone Deacetylase Activity, Hydrolytic Mechanism Protein Lysine Deacetylase Activity Histone Deacetylase Activity B Cell Differentiation Negative Regulation Of Metabolic Process Protein Kinase C Binding Mononuclear Cell Differentiation Leukocyte Activation Cell Activation Regulation Of Myotube Differentiation Histone Deacetylase Complex Regulation Of Cell Differentiation Leukocyte Differentiation Regulation Of Cell Migration Involved In Sprouting Angiogenesis DNA-binding Transcription Factor Binding Regulation Of Primary Metabolic Process Mitochondrial Depolarization B Cell Activation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Developmental Process Lymphocyte Activation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Type II Interferon Production Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Macromolecule Metabolic Process Lymphocyte Differentiation Negative Regulation Of Long-term Synaptic Potentiation Regulation Of RNA Metabolic Process Positive Regulation Of Protein Sumoylation Regulation Of Striated Muscle Cell Differentiation Epigenetic Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Catecholamine Stimulus Negative Regulation Of Myotube Differentiation Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Type II Interferon Production Regulation Of Multicellular Organismal Process Response To Catecholamine Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Superoxide Anion Generation SUMO Transferase Activity Regulation Of Metabolic Process Regulation Of Superoxide Anion Generation Negative Regulation Of Biosynthetic Process Endosome Lumen Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Gene Expression	Spindle Organization Spindle Assembly Cytoskeleton Cytoplasm Identical Protein Binding Spindle Pole Regulation Of Retinoic Acid Receptor Signaling Pathway Regulation Of Metaphase Plate Congression DNA Damage Response White Fat Cell Differentiation Microtubule-based Process Viral Genome Replication