TSHZ3 and TRIM23

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TSHZ3	TRIM23
Gene Name		teashirt zinc finger homeobox 3	tripartite motif containing 23
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Growth Cone	Golgi Membrane Nucleus Lysosomal Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Metal Ion Binding	GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding Ligase Activity GDP Binding Identical Protein Binding
	Biological Process	Metanephros Development Ureteric Bud Development In Utero Embryonic Development Regulation Of Respiratory Gaseous Exchange By Neurological System Process Transcription, DNA-templated Lung Development Negative Regulation Of Transcription, DNA-templated Musculoskeletal Movement Sensory Perception Of Touch Positive Regulation Of Smooth Muscle Cell Differentiation Kidney Morphogenesis Ureteric Peristalsis Ureter Smooth Muscle Cell Differentiation Kidney Smooth Muscle Cell Differentiation	Small GTPase Mediated Signal Transduction Viral Process Protein Ubiquitination Positive Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 19734545) Phospholipid levels (plasma) ( 21829377)
Protein-Protein Interactions		16 interactors: APBB1 CCDC155 CEP63 CEP70 CTBP1 CTBP2 KRT40 MAD1L1 MTUS2 SPAG5 TAX1BP1 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54	137 interactors: AKTIP ANKRD36BP1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 C10orf10 C19orf57 C8orf33 CARD9 CCDC146 CCDC25 CDC20B CDR2 CFAP53 COX5B CREB5 CXCL14 CYTH1 CYTH2 DCX DMC1 DMRT3 DOCK2 EAF2 EXOC3-AS1 FAM103A1 FAM110A FAM133A FAM193B FAM208B FAM83A FAM90A1 FBF1 FHIT FLAD1 FLJ38668 FXR2 GATA2 GEM GGA2 GMCL1P1 GPANK1 GPKOW HAUS1 HOXB5 HSPB7 IQCE IQUB JOSD1 KAT5 KIFC3 KLHL42 KRT6A LGALS8 LINC00526 LINC01018 LMO2 LNX1 LOC729603 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MTFR2 NEK6 NFU1 NXT2 PHF1 PIAS2 PIK3R2 PITX1 PKP4 POLI POLL POM121 PPIL2 PPP1R18 PSMA1 RAD18 RIBC2 RNF126 RNF213 RNF32 RNF34 RSRC2 RTP5 SF1 SH2D4A SIAH1 SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SORBS3 SPG21 STK19 SUMO1P1 TBC1D22B TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TROAP TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2H UBE2I UBE2U UBOX5 USP2 USP20 USP21 UTP23 WDR25 ZC2HC1C ZNF250 ZNF564 ZNF581
Entrez ID		57616	373
HPRD ID		18351	03449
Ensembl ID		ENSG00000121297	ENSG00000113595
Uniprot IDs		Q63HK5	P36406
PDB IDs		2DMI
Enriched GO Terms of Interacting Partners?		Cell Cycle Process White Fat Cell Differentiation Cell Cycle Viral Genome Replication Regulation Of Organelle Organization Organelle Organization Protein K63-linked Ubiquitination Protein Trimerization Regulation Of Cellular Component Organization Mitotic Cell Cycle Process Regulation Of Metaphase Plate Congression Chromosome Localization To Nuclear Envelope Involved In Synapsis Spliceosomal Complex Disassembly Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Negative Regulation Of Thymidylate Synthase Biosynthetic Process Mitotic Cell Cycle Mitotic Nuclear Division Regulation Of Chromosome Segregation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Chromosome Organization Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Protein Metabolic Process Cell Division G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Binding Chromosome Organization Regulation Of Cellular Localization Fat Cell Differentiation Spindle Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Regulation Of Microtubule Cytoskeleton Organization Double-strand Break Repair Negative Regulation Of Calcium Ion Import Positive Regulation Of Chromatin Binding Regulation Of Cytokine Production Viral Process Negative Regulation Of Glial Cell Apoptotic Process Protein Ubiquitination Regulation Of Microtubule-based Process Protein Polyubiquitination Protein Modification By Small Protein Conjugation Interferon-gamma Secretion Viral Life Cycle Negative Regulation Of Histone H4 Acetylation Regulation Of Adaptive Immune Response Regulation Of Chromosome Organization Positive Regulation Of Protein Homodimerization Activity Regulation Of Protein Metabolic Process Regulation Of Transcription, DNA-templated	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Regulation Of Protein Catabolic Process Proteolysis Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Programmed Cell Death Regulation Of Metabolic Process Cellular Response To Stress Positive Regulation Of Metabolic Process Cell Death Death Gene Expression RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia Protein Metabolic Process Cellular Response To Decreased Oxygen Levels Regulation Of Transcription, DNA-templated Regulation Of Proteolysis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Oxygen Levels Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process
Tagcloud ?		chip deep dysregulated dysregulation h3k27me3 homeobox hox hoxb7 hoxc10 hoxc13 hoxd8 irx1 irx4 keratinocytes mark neoplastic okf6 oncomine polycomb prc prc2 repressive rnaseq scc six2 suz12 tert1r transcripts tumorigenic	344r abrogated adaptor antiviral conjugation defense e3 ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Difference) ?		chip deep dysregulated dysregulation h3k27me3 homeobox hox hoxb7 hoxc10 hoxc13 hoxd8 irx1 irx4 keratinocytes mark neoplastic okf6 oncomine polycomb prc prc2 repressive rnaseq scc six2 suz12 tert1r transcripts tumorigenic	344r abrogated adaptor antiviral conjugation defense e3 ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Intersection) ?