ANKRA2

Name	ankyrin repeat family A member 2
Structure
Novel Interactors	1 novel interactors: F2RL1
Interactors	13 interactors: ABL1 APP CDKN2A HDAC4 HDAC5 HDAC9 LRP2 MPL NEK6 PDE3B RFX7 SAMD4A TSHZ3
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton Membrane Protein-containing Complex 3M Complex
	Molecular Function	Protein Binding Protein Kinase Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding Low-density Lipoprotein Particle Receptor Binding
	Biological Process	Regulation Of Gene Expression Regulation Of Protein-containing Complex Assembly
GWAS	Monobrow thickness ( 26926045 )
Entrez ID	57763
HPRD ID	12044
Ensembl ID	ENSG00000164331
Uniprot IDs	Q9H9E1
PDB IDs	3SO8 3V2O 3V2X 3V31 4LG6 4QQI 8CXG 8CXH 8CXI
GO Terms Enriched among Interactors ?	Histone Deacetylase Activity, Hydrolytic Mechanism Protein Lysine Deacetylase Activity Histone Deacetylase Activity B Cell Differentiation Negative Regulation Of Metabolic Process Protein Kinase C Binding Mononuclear Cell Differentiation Leukocyte Activation Cell Activation Regulation Of Myotube Differentiation Histone Deacetylase Complex Regulation Of Cell Differentiation Leukocyte Differentiation Regulation Of Cell Migration Involved In Sprouting Angiogenesis DNA-binding Transcription Factor Binding Regulation Of Primary Metabolic Process Mitochondrial Depolarization B Cell Activation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Developmental Process Lymphocyte Activation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Type II Interferon Production Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Macromolecule Metabolic Process Lymphocyte Differentiation Negative Regulation Of Long-term Synaptic Potentiation Regulation Of RNA Metabolic Process Positive Regulation Of Protein Sumoylation Regulation Of Striated Muscle Cell Differentiation Epigenetic Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Catecholamine Stimulus Negative Regulation Of Myotube Differentiation Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Type II Interferon Production Regulation Of Multicellular Organismal Process Response To Catecholamine Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Superoxide Anion Generation SUMO Transferase Activity Regulation Of Metabolic Process Regulation Of Superoxide Anion Generation Negative Regulation Of Biosynthetic Process Endosome Lumen Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Gene Expression