LRRC4C and CREB3L4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LRRC4C	CREB3L4
Gene Name		leucine rich repeat containing 4C	cAMP responsive element binding protein 3-like 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Membrane Integral Component Of Membrane Cell Junction Postsynaptic Membrane	Golgi Membrane Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription CAMP Response Element Binding
	Biological Process	Regulation Of Axonogenesis	Transcription, DNA-templated Spermatogenesis Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Osteoporosis ( 20548944) Temperament (bipolar disorder) ( 22365631)
Protein-Protein Interactions		3 interactors: CREB3L4 DFNB31 NTNG1	4 interactors: GANAB LRRC4C SLC19A3 SOX9
Entrez ID		57689	148327
HPRD ID		12303	06323
Ensembl ID		ENSG00000148948	ENSG00000143578
Uniprot IDs		Q4JIV9 Q4JIW0 Q9HCJ2	Q8TEY5
PDB IDs		3ZYJ
Enriched GO Terms of Interacting Partners?			Regulation Of Cell Proliferation Involved In Tissue Homeostasis Epithelial Cell Proliferation Involved In Prostatic Bud Elongation Retinal Rod Cell Differentiation Primary Prostatic Bud Elongation Male Germ-line Sex Determination Renal Vesicle Induction Thiamine Transmembrane Transport Primary Sex Determination Astrocyte Fate Commitment Positive Regulation Of Extracellular Matrix Assembly Thiamine Transport Metanephric Nephron Tubule Formation Intestinal Epithelial Structure Maintenance Intrahepatic Bile Duct Development Positive Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Photoreceptor Cell Differentiation Cellular Response To Heparin Regulation Of Extracellular Matrix Assembly Ureter Urothelium Development Response To Heparin Ureter Morphogenesis Ureter Smooth Muscle Cell Differentiation Chondrocyte Hypertrophy Metanephric Tubule Formation Regulation Of Mesenchymal Stem Cell Differentiation Thiamine-containing Compound Metabolic Process Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Common Bile Duct Development Metanephric Nephron Tubule Morphogenesis Limb Bud Formation Otic Vesicle Formation Pyrimidine-containing Compound Transmembrane Transport Positive Regulation Of Male Gonad Development Otic Vesicle Morphogenesis Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process Metanephric Tubule Morphogenesis Camera-type Eye Photoreceptor Cell Differentiation Male Sex Determination Maintenance Of Gastrointestinal Epithelium Otic Vesicle Development Ureter Development ERK1 And ERK2 Cascade Vitamin Transmembrane Transport Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Heart Valve Formation Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Metanephric Nephron Tubule Development Regulation Of Neuron Differentiation
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