ZBTB4 and SPATC1L

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		ZBTB4	SPATC1L
Description		zinc finger and BTB domain containing 4	spermatogenesis and centriole associated 1 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body	Cytoplasm Centrosome Sperm Head-tail Coupling Apparatus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Methyl-CpNpG Binding Protein Kinase Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding	Protein Binding Protein Kinase A Regulatory Subunit Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription DNA Damage Response Negative Regulation Of DNA-templated Transcription	Spermatogenesis Actin Polymerization Or Depolymerization Positive Regulation Of CAMP/PKA Signal Transduction
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Brain morphology (MOSTest) ( 32665545) Corpus callosum posterior volume ( 31530798) Diverticular disease ( 30177863) Height ( 25282103 31562340) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Refractive error ( 32231278) Serum uric acid levels ( 30993211) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		18 interacting genes: ANXA2 BANP CALCOCO2 CBFA2T3 CCDC57 CEP70 CEP76 CYSRT1 GOLGA2 HIPK2 HOMER3 KLHL12 PDE4DIP PIBF1 POU6F2 SPATC1L TP53BP2 TRIM23	51 interacting genes: ACOT7 ARL4A ARMC7 ATPAF2 CABP2 CLTC DISC1 EXOSC8 FOXN1 FSD2 GOLGA6A GTF3C6 HOOK2 IKZF1 KIFC3 KRT40 KRTAP5-9 LZTS2 MISP MTUS2 MYO15B NCK2 NUTF2 NXF1 PARN PHC2 PHF11 PIAS2 PICK1 PINK1 PLEC PNMA1 POLR1C PPP1CB PPP1CC QARS1 RAD51D RBMY1F RBMY1J REL SIAH1 SNRNP70 SYCE1 TCF4 TEKT4 TRIM27 TRMO TSR2 UBL5 ZBTB4 ZBTB8B
Entrez ID		57659	84221
HPRD ID		11693	10753
Ensembl ID		ENSG00000174282	ENSG00000160284
Uniprot IDs		B3KVD4 Q9P1Z0	Q9H0A9
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Centrosome Microtubule Organizing Center Organization Microtubule Organizing Center Cytoplasm Microtubule Nucleation Cytoskeleton Centriolar Satellite Negative Regulation Of Catabolic Process Spindle Organization COPII-coated ER To Golgi Transport Vesicle	Protein Binding Cytoskeleton Identical Protein Binding Nucleus RNA Metabolic Process PTW/PP1 Phosphatase Complex Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing
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