SLAIN2 and MAPRE2

Number of citations of the paper that reports this interaction (PubMedID 30217970)
38

Data Source:
BioGRID (two hybrid)

		SLAIN2	MAPRE2
Description		SLAIN motif family member 2	microtubule associated protein RP/EB family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoskeleton Microtubule Cytoskeleton Microtubule Plus-end	Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Cytoplasmic Microtubule Focal Adhesion Microtubule Cytoskeleton Microtubule Plus-end Spindle Midzone
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding
	Biological Process	Microtubule Nucleation Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Polymerization Cytoplasmic Microtubule Organization	Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of ARF Protein Signal Transduction Protein Localization To Microtubule Spindle Assembly Cell Division Positive Regulation Of Keratinocyte Migration Positive Regulation Of Focal Adhesion Disassembly
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Uterine fibroids ( 30194396)	Brugada syndrome ( 35210625) Cerebrospinal fluid AB1-42 levels ( 26252872) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Facial morphology ( 29921221) Metabolite levels ( 23823483)
Interacting Genes		12 interacting genes: APP CASK CEBPA CKAP5 DAPK1 MAPRE2 PTPRD SGO2 SMURF1 SRPK1 SRPK2 TULP3	25 interacting genes: APC APP AURKA AURKB CASK CDK2 CDK4 CLASP2 CLIP1 DDIT4L FBXO7 GTSE1 LMNA LMO2 LNX1 MAPRE3 NIF3L1 PAXIP1 RBM10 RBM6 SLAIN2 TRAF1 TRAIP TXN2 UBC
Entrez ID		57606	10982
HPRD ID		13863	16157
Ensembl ID		ENSG00000109171	ENSG00000166974
Uniprot IDs		A0A024R9T6 Q9P270	Q15555
PDB IDs		3RDV
Enriched GO Terms of Interacting Partners?		Nuclear Matrix Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Microtubule Plus-end Microtubule Plus-end Binding Positive Regulation Of Proteolysis Positive Regulation Of Cellular Component Organization Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Catabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Nucleolus RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Kinase Activity Protein Kinase Activity DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Positive Regulation Of Viral Genome Replication Microtubule Plus End Polymerase Engulfment Of Target By Autophagosome Positive Regulation Of Viral Process Acetylcholine Receptor Activator Activity PTB Domain Binding Signaling Receptor Binding Cellular Developmental Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Neuron Apoptotic Process Regulation Of Proteolysis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus G Protein-coupled Receptor Binding Defense Response Cell Surface Receptor Signaling Pathway Lipoprotein Particle Positive Regulation Of Cell Differentiation Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Signal Transduction Astrocyte Activation Involved In Immune Response Microglia Development	Regulation Of Microtubule Polymerization Or Depolymerization Microtubule Plus-end Binding Regulation Of Microtubule-based Process Regulation Of Microtubule Cytoskeleton Organization Microtubule Cytoskeleton Microtubule-based Process Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Supramolecular Fiber Organization Cytoplasmic Microtubule Regulation Of Microtubule Polymerization Centrosome Microtubule Cytoskeleton Organization Kinetochore Cell Cycle Phase Transition Microtubule Plus-end Spindle Midzone Regulation Of Cell Cycle Process Microtubule Spindle Assembly Regulation Of Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Microtubule Depolymerization Positive Regulation Of Cellular Component Organization Cytoskeleton Chromosome Passenger Complex Spindle Microtubule Microtubule Binding Regulation Of Organelle Organization Positive Regulation Of Mitotic Cell Cycle Cell Division Membraneless Organelle Assembly Mitotic Cell Cycle Phase Transition Ubiquitin Protein Ligase Binding Cell Cycle G2/M Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Spindle Organization Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cytoskeleton Organization Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cell Cycle Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Metabolic Process Negative Regulation Of Cell Cycle G1/S Phase Transition Identical Protein Binding Regulation Of Cell Cycle G1/S Phase Transition Protein Serine Kinase Activity Nuclear Lamina
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