PITPNM2 and CPNE1

Number of citations of the paper that reports this interaction (PMID 12522145)
20

Data Source:
HPRD (in vitro)

		PITPNM2	CPNE1
Gene Name		phosphatidylinositol transfer protein, membrane-associated 2	copine I
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Lipid Binding	Phosphatidylserine Binding Transporter Activity Calcium-dependent Phospholipid Binding
	Biological Process	Transport Metabolic Process	Lipid Metabolic Process Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS		Platelet counts ( 21507922)
Protein-Protein Interactions		3 interactors: CPNE1 CPNE4 PTK2B	18 interactors: ACTB BCOR BUB3 CCDC22 CPNE4 LIG4 MAP2K1 MYCBP PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 STK3 UBE2M UBE2O WTAP
Entrez ID		57605	8904
HPRD ID		08335	05014
Ensembl ID		ENSG00000090975	ENSG00000214078
Uniprot IDs		Q9BZ72 Q9UF51	B0QZ18 Q99829
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of CGMP-mediated Signaling Marginal Zone B Cell Differentiation Positive Regulation Of B Cell Chemotaxis Activation Of Janus Kinase Activity Regulation Of Inositol Trisphosphate Biosynthetic Process Activation Of Rac GTPase Activity Regulation Of Macrophage Chemotaxis Stress Fiber Assembly Glial Cell Proliferation Mature B Cell Differentiation Involved In Immune Response Signal Complex Assembly Positive Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Bone Mineralization Mature B Cell Differentiation Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Negative Regulation Of Biomineral Tissue Development Regulation Of CGMP Biosynthetic Process Response To Immobilization Stress Positive Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Monooxygenase Activity Oocyte Maturation Negative Regulation Of Potassium Ion Transport Positive Regulation Of Phosphatidylinositol 3-kinase Activity Response To Lithium Ion Regulation Of Lymphocyte Migration Regulation Of CGMP Metabolic Process Focal Adhesion Assembly Blood Vessel Endothelial Cell Migration Positive Regulation Of Excitatory Postsynaptic Membrane Potential Negative Regulation Of Muscle Cell Apoptotic Process Bone Resorption Regulation Of Establishment Of Cell Polarity Peptidyl-tyrosine Autophosphorylation Regulation Of Nitric-oxide Synthase Activity Tumor Necrosis Factor-mediated Signaling Pathway Activation Of Rho GTPase Activity Positive Regulation Of Oxidoreductase Activity Regulation Of Actin Cytoskeleton Reorganization Regulation Of Establishment Or Maintenance Of Cell Polarity Positive Regulation Of Membrane Potential Regulation Of Calcium-mediated Signaling Ionotropic Glutamate Receptor Signaling Pathway Oocyte Development Adherens Junction Assembly Oocyte Differentiation B Cell Activation Involved In Immune Response Response To Cocaine Long-term Synaptic Potentiation Regulation Of Phosphatidylinositol 3-kinase Activity Cell-substrate Junction Assembly	Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Protein Heterooligomerization Regulation Of Cellular Process Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Regulation Of Cellular Component Organization Golgi To Plasma Membrane Transport Regulation Of Organelle Organization In Utero Embryonic Development Protein Monoubiquitination Generation Of Neurons Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cell Cycle Process Actin Filament Capping Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Neurogenesis Negative Regulation Of Histone H3-K36 Methylation DNA Ligation Involved In DNA Recombination Positive Regulation Of Cell Death Anatomical Structure Morphogenesis Negative Regulation Of Actin Filament Depolymerization Regulation Of Intracellular Signal Transduction Mitotic Cell Cycle Process Cellular Protein Metabolic Process Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Mitotic Nuclear Division Cellular Component Assembly Negative Regulation Of Tooth Mineralization Protein Metabolic Process Mitotic Cell Cycle Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Polymerization Post-Golgi Vesicle-mediated Transport Regulation Of Signal Transduction Negative Regulation Of Chromosome Organization Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Protein Complex Disassembly Axon Guidance Positive Regulation Of Cell Differentiation Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Apoptotic Process Regulation Of Protein Depolymerization
Tagcloud ?			affect arrangement cdnas coding connection conservation copine courses ests evolutionary exons genome genomic indicates initiated motif pairs phenomenon promoters rbm12 sequences share sharing shed splicing tags totally utr zebrafish
Tagcloud (Difference) ?			affect arrangement cdnas coding connection conservation copine courses ests evolutionary exons genome genomic indicates initiated motif pairs phenomenon promoters rbm12 sequences share sharing shed splicing tags totally utr zebrafish
Tagcloud (Intersection) ?