WDR48 and FANCI

Number of citations of the paper that reports this interaction (PMID 21896657)
20

Data Source:
BioGRID (pull down, affinity chromatography technology)

		WDR48	FANCI
Gene Name		WD repeat domain 48	Fanconi anemia, complementation group I
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Lysosome Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding	DNA Binding Protein Binding DNA Polymerase Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Spermatogenesis Single Fertilization Viral Process Protein Deubiquitination Multicellular Organism Growth Skin Development Embryonic Organ Development Skeletal System Morphogenesis Homeostasis Of Number Of Cells Positive Regulation Of Epithelial Cell Proliferation Seminiferous Tubule Development Regulation Of Protein Monoubiquitination	DNA Repair Cell Cycle Positive Regulation Of Protein Ubiquitination
Pathways			Fanconi Anemia pathway Regulation of the Fanconi anemia pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: FANCI PAXIP1 PCNA WDR20	4 interactors: APP FANCD2 FANCL WDR48
Entrez ID		57599	55215
HPRD ID		11146	13339
Ensembl ID		ENSG00000114742	ENSG00000140525
Uniprot IDs		Q8TAF3	B3KNW8 Q9NVI1
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Positive Regulation Of Protein Ubiquitination Positive Regulation Of DNA Metabolic Process Positive Regulation Of Deoxyribonuclease Activity Positive Regulation Of Histone H3-K36 Methylation Regulation Of Protein Ubiquitination Leading Strand Elongation Cellular Response To Stress DNA Recombination Chorion Development Positive Regulation Of Cellular Metabolic Process Translesion Synthesis Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Nucleotide-excision Repair, DNA Gap Filling Positive Regulation Of DNA-templated Transcription, Initiation Telomere Maintenance Via Semi-conservative Replication Postreplication Repair Positive Regulation Of Histone Acetylation Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of DNA-templated Transcription, Initiation Regulation Of Histone H3-K4 Methylation Nuclear DNA Replication Telomere Maintenance Via Recombination Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Metabolic Process Positive Regulation Of Isotype Switching Response To Stress Positive Regulation Of Protein Acetylation Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Cardiovascular System Development Histone H3-K4 Methylation Regulation Of Isotype Switching Positive Regulation Of Protein Modification Process Positive Regulation Of Immunoglobulin Mediated Immune Response Adipose Tissue Development Positive Regulation Of Histone Methylation Positive Regulation Of Immunoglobulin Production Transcription-coupled Nucleotide-excision Repair Chromosome Organization Regulation Of Histone Acetylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Histone Methylation Positive Regulation Of Nuclease Activity Nucleobase-containing Compound Metabolic Process	Sexual Reproduction Reproduction Reproductive Process DNA Repair Gamete Generation Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Cellular Response To DNA Damage Stimulus Regulation Of Protein Monoubiquitination Synaptic Growth At Neuromuscular Junction DNA Metabolic Process Response To Stress Collateral Sprouting In Absence Of Injury Single Organism Reproductive Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Stress Axon Choice Point Recognition Nucleobase-containing Compound Metabolic Process Neuron Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Growth Seminiferous Tubule Development Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Stimulus RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Monoubiquitination Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Response To Gamma Radiation Cellular Protein Modification Process
Tagcloud ?			affymetrix anthracycline anthracyclines atm bc bimodal bub1 damaging enable fan1 fashion impair mnat1 msh2 msh6 mtmr15 parp2 pcna pms2 polq recql4 regimens residual rpa3 sensitizing survive taxane top2a ube2v2
Tagcloud (Difference) ?			affymetrix anthracycline anthracyclines atm bc bimodal bub1 damaging enable fan1 fashion impair mnat1 msh2 msh6 mtmr15 parp2 pcna pms2 polq recql4 regimens residual rpa3 sensitizing survive taxane top2a ube2v2
Tagcloud (Intersection) ?