ZNF398 and ELMO1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZNF398	ELMO1
Gene Name		zinc finger protein 398	engulfment and cell motility 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane
	Molecular Function	DNA Binding Metal Ion Binding	Protein Binding SH3 Domain Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Phagocytosis, Engulfment Apoptotic Process Movement Of Cell Or Subcellular Component Viral Process Rac Protein Signal Transduction Actin Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Defense Response To Virus By Virus
Pathways		Generic Transcription Pathway	Signaling by VEGF HIV Infection Host Interactions of HIV factors The role of Nef in HIV-1 replication and disease pathogenesis Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System Nef and signal transduction
Drugs
Diseases
GWAS			Alzheimer's disease (cognitive decline) ( 23535033) Anticoagulant levels ( 22216198) Breast size ( 22747683) Celiac disease ( 20190752) Celiac disease and Rheumatoid arthritis ( 21383967) QT interval ( 20031603) Response to treatment for acute lymphoblastic leukemia ( 19176441) Type 2 diabetes nephropathy ( 17653210)
Protein-Protein Interactions		13 interactors: C1orf109 CIB3 CLK2 DGCR6 ELMO1 ESR1 GPATCH2L LOC155060 MAGOHB MFAP1 NDE1 OPTN PLEKHF2	6 interactors: DOCK1 FGD1 HCK RHOG TRIM54 ZNF398
Entrez ID		57541	9844
HPRD ID		18336	12102
Ensembl ID		ENSG00000197024	ENSG00000155849
Uniprot IDs		B4DXA9 Q8TD17	A4D1X5 Q92556
PDB IDs			2RQR 2VSZ 3A98
Enriched GO Terms of Interacting Partners?		Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Respiratory Burst After Phagocytosis Small GTPase Mediated Signal Transduction Integrin-mediated Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Leukocyte Migration Involved In Immune Response Positive Regulation Of GTPase Activity Regulation Of Cellular Component Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of GTPase Activity Regulation Of Cell Shape Cell Migration Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Respiratory Burst Involved In Defense Response Positive Regulation Of Hydrolase Activity Positive Regulation Of Rho GTPase Activity Regulation Of Podosome Assembly Phagocytosis Fc Receptor Signaling Pathway Regulation Of Rho GTPase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Projection Organization Signal Transduction Locomotion Regulation Of Rho Protein Signal Transduction Respiratory Burst Developmental Process Activation Of Rac GTPase Activity Phagocytosis, Engulfment Immune Response-regulating Cell Surface Receptor Signaling Pathway Signaling Positive Regulation Of Actin Cytoskeleton Reorganization Axon Guidance Cell Communication Movement Of Cell Or Subcellular Component Blood Coagulation Positive Regulation Of Catalytic Activity Regulation Of Ruffle Assembly Membrane Invagination Filopodium Assembly Hemostasis Positive Regulation Of Ras GTPase Activity Cell Differentiation Positive Regulation Of Metabolic Process Rac Protein Signal Transduction Immune Response-regulating Signaling Pathway Regulation Of Cell Morphogenesis Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane
Tagcloud ?			ahsa2 cd coeliac ddx59 egenes eprobes eqtl eqtls esnps harbour il18rap implies nominal nsf overlapped park7 pbmc rs12727642 rs13003464 rs2074404 rs2298428 rs296547 rs6974491 rs842647 rs917997 snps thymic thymus ube2l3
Tagcloud (Difference) ?			ahsa2 cd coeliac ddx59 egenes eprobes eqtl eqtls esnps harbour il18rap implies nominal nsf overlapped park7 pbmc rs12727642 rs13003464 rs2074404 rs2298428 rs296547 rs6974491 rs842647 rs917997 snps thymic thymus ube2l3
Tagcloud (Intersection) ?