NDRG2 and MOB2

Number of citations of the paper that reports this interaction (PMID 15067004)
19

Data Source:
HPRD (in vivo, in vitro)

		NDRG2	MOB2
Gene Name		NDRG family member 2	MOB kinase activator 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Microtubule Organizing Center Cytosol Growth Cone Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Nucleus Nucleolus Cytoplasm Neuron Projection Terminus Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Protein Binding	Metal Ion Binding
	Biological Process	Negative Regulation Of Cytokine Production Regulation Of Vascular Endothelial Growth Factor Production Wnt Signaling Pathway Substantia Nigra Development Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Platelet-derived Growth Factor Production	Positive Regulation Of Protein Phosphorylation Positive Regulation Of Neuron Projection Development Actin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ATP1B1 CLN8 CTDP1 MOB2	2 interactors: NDRG2 STK38
Entrez ID		57447	81532
HPRD ID		17630	17581
Ensembl ID		ENSG00000165795
Uniprot IDs		B4DE86 Q9UN36	Q70IA6
PDB IDs		2XMQ 2XMR 2XMS
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Calcium:sodium Antiporter Activity L-glutamate Uptake Involved In Synaptic Transmission Positive Regulation Of Potassium Ion Import Positive Regulation Of Sodium Ion Export From Cell Protein Transport Into Plasma Membrane Raft Protein Localization To Plasma Membrane Raft Age-dependent Response To Oxidative Stress Sodium Ion Export From Cell Sodium Ion Export Somatic Motor Neuron Differentiation Cellular Potassium Ion Homeostasis L-glutamate Import Protein Transport Into Membrane Raft Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Exit From Mitosis Protein Localization To Membrane Raft Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Cell Communication By Electrical Coupling Involved In Cardiac Conduction Neurotransmitter Uptake Cellular Sodium Ion Homeostasis Relaxation Of Cardiac Muscle Membrane Repolarization Neurofilament Cytoskeleton Organization Cell Communication By Electrical Coupling Potassium Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transport Neuromuscular Process Controlling Posture Amino Acid Import Positive Regulation Of Potassium Ion Transmembrane Transport Protein Transport Within Lipid Bilayer Relaxation Of Muscle Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Sodium Ion Homeostasis Potassium Ion Import Regulation Of Potassium Ion Transmembrane Transporter Activity L-glutamate Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Positive Regulation Of ATPase Activity Photoreceptor Cell Maintenance Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport Social Behavior Intermediate Filament Cytoskeleton Organization Regulation Of ATPase Activity	Negative Regulation Of MAPK Cascade Negative Regulation Of Phosphorylation Negative Regulation Of Intracellular Signal Transduction Regulation Of Platelet-derived Growth Factor Production Regulation Of MAPK Cascade Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Phosphorylation Substantia Nigra Development Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Phosphorus Metabolic Process Neural Nucleus Development Regulation Of Intracellular Signal Transduction Negative Regulation Of MAP Kinase Activity Midbrain Development Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Signal Transduction Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cytokine Production Regulation Of Signaling
Tagcloud ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	atm binder biochemically competing damage damaged ddr enigmatic exogenously facilitating hmob1 hmob2 manipulations mechanistic mobs mps mre11 mrn nbs1 ndr ndrs partners performs rad50 revealing sensor signalling supports unexpectedly
Tagcloud (Difference) ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	atm binder biochemically competing damage damaged ddr enigmatic exogenously facilitating hmob1 hmob2 manipulations mechanistic mobs mps mre11 mrn nbs1 ndr ndrs partners performs rad50 revealing sensor signalling supports unexpectedly
Tagcloud (Intersection) ?