NDRG2 and ATP1B1

Number of citations of the paper that reports this interaction (PMID 21771789)
5

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		NDRG2	ATP1B1
Gene Name		NDRG family member 2	ATPase, Na+/K+ transporting, beta 1 polypeptide
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Microtubule Organizing Center Cytosol Growth Cone Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Intercalated Disc Basolateral Plasma Membrane Apical Plasma Membrane Vesicle Sarcolemma Extracellular Vesicular Exosome
	Molecular Function	Molecular_function Protein Binding	ATPase Activator Activity Sodium:potassium-exchanging ATPase Activity Protein Binding MHC Class II Protein Complex Binding ATPase Binding
	Biological Process	Negative Regulation Of Cytokine Production Regulation Of Vascular Endothelial Growth Factor Production Wnt Signaling Pathway Substantia Nigra Development Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Platelet-derived Growth Factor Production	Response To Hypoxia Cellular Calcium Ion Homeostasis Cellular Sodium Ion Homeostasis Cell Adhesion Blood Coagulation Potassium Ion Import Regulation Of Gene Expression Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Export From Cell Protein Transport Into Plasma Membrane Raft Protein Stabilization Leukocyte Migration Transmembrane Transport Relaxation Of Cardiac Muscle Cardiac Muscle Contraction Protein Localization To Plasma Membrane Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export From Cell Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of Potassium Ion Import
Pathways			Ion transport by P-type ATPases Ion channel transport Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			QT interval ( 23166209 19305409)
Protein-Protein Interactions		4 interactors: ATP1B1 CLN8 CTDP1 MOB2	17 interactors: BACE1 BARD1 BRCA1 CRIP2 DDAH2 EGFR EZH2 FXYD1 FXYD7 GCH1 KMT2B LRIF1 NDRG2 PAXIP1 PSME1 TRMT2A USP4
Entrez ID		57447	481
HPRD ID		17630	01663
Ensembl ID		ENSG00000165795	ENSG00000143153
Uniprot IDs		B4DE86 Q9UN36	A3KLL5 A6NGH2 P05026
PDB IDs		2XMQ 2XMR 2XMS
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Calcium:sodium Antiporter Activity L-glutamate Uptake Involved In Synaptic Transmission Positive Regulation Of Potassium Ion Import Positive Regulation Of Sodium Ion Export From Cell Protein Transport Into Plasma Membrane Raft Protein Localization To Plasma Membrane Raft Age-dependent Response To Oxidative Stress Sodium Ion Export From Cell Sodium Ion Export Somatic Motor Neuron Differentiation Cellular Potassium Ion Homeostasis L-glutamate Import Protein Transport Into Membrane Raft Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Exit From Mitosis Protein Localization To Membrane Raft Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Cell Communication By Electrical Coupling Involved In Cardiac Conduction Neurotransmitter Uptake Cellular Sodium Ion Homeostasis Relaxation Of Cardiac Muscle Membrane Repolarization Neurofilament Cytoskeleton Organization Cell Communication By Electrical Coupling Potassium Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transport Neuromuscular Process Controlling Posture Amino Acid Import Positive Regulation Of Potassium Ion Transmembrane Transport Protein Transport Within Lipid Bilayer Relaxation Of Muscle Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Sodium Ion Homeostasis Potassium Ion Import Regulation Of Potassium Ion Transmembrane Transporter Activity L-glutamate Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Positive Regulation Of ATPase Activity Photoreceptor Cell Maintenance Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport Social Behavior Intermediate Filament Cytoskeleton Organization Regulation Of ATPase Activity	Regulation Of Histone H3-K4 Methylation Regulation Of Histone Methylation Regulation Of Protein Ubiquitination Protein K6-linked Ubiquitination Negative Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Histone H3-K4 Methylation Histone Lysine Methylation Signal Transduction In Response To DNA Damage Peptidyl-lysine Methylation Nitrogen Compound Metabolic Process Nitric Oxide Biosynthetic Process Regulation Of Protein Metabolic Process Reactive Oxygen Species Metabolic Process Signal Transduction By P53 Class Mediator Positive Regulation Of Histone Acetylation Histone Methylation Regulation Of Histone Modification Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Positive Regulation Of Protein Ubiquitination Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of DNA Metabolic Process Regulation Of Reactive Oxygen Species Metabolic Process Methylation Nitric Oxide Metabolic Process Positive Regulation Of Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of Cellular Protein Metabolic Process Protein Polyubiquitination Histone H3-K4 Methylation Protein Methylation Positive Regulation Of Histone Methylation Positive Regulation Of DNA Repair Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Regulation Of Cellular Ketone Metabolic Process Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Regulation Of Chromosome Organization Regulation Of Gene Expression, Epigenetic Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Histone Acetylation Negative Regulation Of Cell Death
Tagcloud ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	activin belongs bip caps elusive folding grp78 homeobox hspa5 hspa5mo knock lhx1 lim malformation morphants morpholino mos multifunctional oligonucleotides participates pax2 pronephric pronephros rescued residing serves specification unfolded xenopus
Tagcloud (Difference) ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	activin belongs bip caps elusive folding grp78 homeobox hspa5 hspa5mo knock lhx1 lim malformation morphants morpholino mos multifunctional oligonucleotides participates pax2 pronephric pronephros rescued residing serves specification unfolded xenopus
Tagcloud (Intersection) ?