LYRM1 and MTAP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LYRM1	MTAP
Gene Name		LYR motif containing 1	methylthioadenosine phosphorylase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrion Intercellular Bridge	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function		Phosphorylase Activity S-methyl-5-thioadenosine Phosphorylase Activity
	Biological Process		Sulfur Amino Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Purine Ribonucleoside Salvage Polyamine Metabolic Process Nicotinamide Riboside Catabolic Process L-methionine Biosynthetic Process From Methylthioadenosine Methylation Response To Testosterone Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process
Pathways			Metabolism of polyamines Sulfur amino acid metabolism Methionine salvage pathway Metabolism of amino acids and derivatives
Drugs			Adenine (1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol Formycin 5\'-Deoxy-5\'-Methylthioadenosine 5\'-Deoxy-5\'-(Methylthio)-Tubercidin
Diseases
GWAS			Coronary heart disease ( 21606135) Cutaneous nevi ( 19578365) Melanoma ( 21983787)
Protein-Protein Interactions		1 interactors: MTAP	6 interactors: CDC25A CENPH FOLH1 LYRM1 MYLIP RELB
Entrez ID		57149	4507
HPRD ID		14254	01134
Ensembl ID		ENSG00000102897	ENSG00000099810
Uniprot IDs		O43325	B4DUC8 Q13126
PDB IDs			1CB0 1CG6 1K27 1SD1 1SD2 3LN5 3OZC 3OZD 3OZE
Enriched GO Terms of Interacting Partners?		Purine Ribonucleoside Salvage L-methionine Biosynthetic Process From Methylthioadenosine L-methionine Salvage Methionine Biosynthetic Process Methionine Metabolic Process Sulfur Amino Acid Biosynthetic Process Purine-containing Compound Salvage Polyamine Metabolic Process Response To Testosterone Sulfur Amino Acid Metabolic Process Cellular Biogenic Amine Metabolic Process Cellular Amino Acid Biosynthetic Process Amine Metabolic Process Purine Nucleoside Metabolic Process Alpha-amino Acid Metabolic Process Nucleoside Metabolic Process Sulfur Compound Metabolic Process Methylation Cellular Amino Acid Metabolic Process Response To Steroid Hormone Nucleobase-containing Small Molecule Metabolic Process
Tagcloud ?			9p 9p21 abilities accounts aggressiveness alanosine anchorage attributable confers hemizygous homozygous immunoexpression inactivated losses methylthioadenosine myxofibrosarcoma myxofibrosarcomas pathogenically phosphorylase portended preserved recurrently reexpressing reexpression reverted spanning umbilical unfavorable xenografts
Tagcloud (Difference) ?			9p 9p21 abilities accounts aggressiveness alanosine anchorage attributable confers hemizygous homozygous immunoexpression inactivated losses methylthioadenosine myxofibrosarcoma myxofibrosarcomas pathogenically phosphorylase portended preserved recurrently reexpressing reexpression reverted spanning umbilical unfavorable xenografts
Tagcloud (Intersection) ?