MAN1C1 and MYG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAN1C1	MYG1
Description		mannosidase alpha class 1C member 1	MYG1 exonuclease
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Membrane Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase Activity Calcium Ion Binding Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Metal Ion Binding	3'-5'-RNA Exonuclease Activity Nuclease Activity Protein Binding Hydrolase Activity
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Protein N-linked Glycosylation N-glycan Processing ERAD Pathway Golgi Apparatus Mannose Trimming	Mitochondrial RNA Metabolic Process RRNA Processing MRNA Processing Locomotory Exploration Behavior
Pathways		Intra-Golgi traffic Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Blood protein levels ( 30072576) Femur bone mineral density x serum urate levels interaction ( 34046847) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		3 interacting genes: FARS2 MYG1 SMAD9	38 interacting genes: AGTRAP ALDH7A1 AP1B1 APOA5 ARL6IP1 BSND CDS2 CMTM5 COPS5 CPLX2 CTSA DDIT4L DESI2 DGAT2L6 FAM9B GADD45GIP1 GRB2 HORMAD1 HSPB1 MAN1C1 METTL9 NDN PLIN3 RHBDD2 RXRB SFT2D1 SKIL SLC17A9 SPG21 SUMO2 SYNGR1 SYP TLCD4 TMEM229B TMEM239 TNMD WWOX YIF1A
Entrez ID		57134	60314
HPRD ID		14354	10705
Ensembl ID		ENSG00000117643	ENSG00000139637
Uniprot IDs		A6NGN6 Q59G34 Q9NR34	Q9HB07
PDB IDs
Enriched GO Terms of Interacting Partners?		Phenylalanine-tRNA Ligase Activity Phenylalanyl-tRNA Aminoacylation Heteromeric SMAD Protein Complex SMAD Protein Complex Mitochondrial Matrix I-SMAD Binding Locomotory Exploration Behavior SMAD Protein Signal Transduction Cellular Response To BMP Stimulus TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity RNA Processing TRNA Aminoacylation Exploration Behavior 3'-5'-RNA Exonuclease Activity Mitochondrial RNA Metabolic Process
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