MAN1C1

Description		mannosidase alpha class 1C member 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Membrane Extracellular Exosome
	Molecular Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase Activity Calcium Ion Binding Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Metal Ion Binding
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Protein N-linked Glycosylation N-glycan Processing ERAD Pathway Golgi Apparatus Mannose Trimming
Pathways		Intra-Golgi traffic Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Blood protein levels ( 30072576) Femur bone mineral density x serum urate levels interaction ( 34046847) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		3 interacting genes: FARS2 MYG1 SMAD9
Entrez ID		57134
HPRD ID		14354
Ensembl ID		ENSG00000117643
Uniprot IDs		A6NGN6 Q59G34 Q9NR34
PDB IDs
Enriched GO Terms of Interacting Partners?		Phenylalanine-tRNA Ligase Activity Phenylalanyl-tRNA Aminoacylation Heteromeric SMAD Protein Complex SMAD Protein Complex Mitochondrial Matrix I-SMAD Binding Locomotory Exploration Behavior SMAD Protein Signal Transduction Cellular Response To BMP Stimulus TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity RNA Processing TRNA Aminoacylation Exploration Behavior 3'-5'-RNA Exonuclease Activity Mitochondrial RNA Metabolic Process
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