PLAAT1 and GPANK1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLAAT1	GPANK1
Description		phospholipase A and acyltransferase 1	G-patch domain and ankyrin repeats 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Lumen Cytoplasm Mitochondrion Lysosome Endoplasmic Reticulum Cytosol Membrane
	Molecular Function	Phospholipase Activity Phospholipase A2 Activity Protein Binding O-acyltransferase Activity Phospholipase A1 Activity N-acyltransferase Activity Transferase Activity Hydrolase Activity	Nucleic Acid Binding Protein Binding
	Biological Process	Lipid Metabolic Process Lipid Catabolic Process Phosphatidylcholine Metabolic Process N-acylphosphatidylethanolamine Metabolic Process Lens Fiber Cell Differentiation Organelle Disassembly
Pathways		Acyl chain remodelling of PE
Drugs
Diseases
GWAS			Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Febrile seizures (MMR vaccine-related) ( 25344690) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		7 interacting genes: APP DNAAF19 GPANK1 HGS TLX3 UBQLN1 ZIC1	90 interacting genes: ABI2 AKAP8L ANAPC11 AP1B1 AP2B1 APP BAG4 C1QTNF2 CADPS CCDC184 CCDC33 CCDC85B CEACAM6 CIMIP2B CYSRT1 DDI1 DHX15 DISC1 ECM1 EFS FTO GOLGA2 GOLGA6L9 GPRASP3 GRB2 HNRNPH1 HOMEZ HSF2BP HYI INKA1 INSC KANK2 KATNBL1 KCTD9 KRT75 KRTAP10-8 KRTAP12-2 KRTAP13-3 KRTAP19-5 KRTAP19-6 LDOC1 LIG4 LZTS2 MAGED1 MAGOHB MDFI MEOX1 MEOX2 METTL27 METTL6 MID2 MORN3 NADSYN1 NFKBID NR1H3 NUTM1 OIP5 PATZ1 PAX6 PBX4 PFDN5 PLAAT1 PNMA1 PPARA PPP4C PRDM6 PTH1R RIMBP3C RTL8C SORBS3 SPATA2 STMN3 STX5 TEPSIN TFCP2 TLE5 TRAF2 TRAPPC2L TRIM23 TRIM27 TSC1 TTC19 TTC23 VBP1 VHL ZBTB16 ZBTB8OS ZMAT5 ZNF688 ZRANB1
Entrez ID		57110	7918
HPRD ID		07577	00810
Ensembl ID		ENSG00000127252	ENSG00000204438
Uniprot IDs		Q9HDD0	A0A024RCU2 A0A0G2JHL1 A0A1U9X7R4 B2RA66 O95872
PDB IDs
Enriched GO Terms of Interacting Partners?		Central Nervous System Development Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Adult Locomotory Behavior Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Adult Behavior Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Protein Catabolic Process Lipoprotein Particle Regulation Of Protein Localization To Nucleus Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Regulation Of Transport Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling ESCRT-0 Complex Phagocytic Vesicle Lumen Macroautophagy Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Neuron Differentiation Regulation Of Toll Signaling Pathway Locomotory Behavior Positive Regulation Of Proteolysis Axon Choice Point Recognition	Protein Binding Nucleus Regulation Of Supramolecular Fiber Organization Asymmetric Cell Division
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