PLAAT1 and DNAAF19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLAAT1	DNAAF19
Description		phospholipase A and acyltransferase 1	dynein axonemal assembly factor 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Lumen Cytoplasm Mitochondrion Lysosome Endoplasmic Reticulum Cytosol Membrane	Extracellular Region Cytoplasm Cilium Axoneme Motile Cilium Outer Dynein Arm Cell Projection
	Molecular Function	Phospholipase Activity Phospholipase A2 Activity Protein Binding O-acyltransferase Activity Phospholipase A1 Activity N-acyltransferase Activity Transferase Activity Hydrolase Activity	Protein Binding Protein Homodimerization Activity
	Biological Process	Lipid Metabolic Process Lipid Catabolic Process Phosphatidylcholine Metabolic Process N-acylphosphatidylethanolamine Metabolic Process Lens Fiber Cell Differentiation Organelle Disassembly	Heart Looping Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Determination Of Left/right Symmetry Cell Projection Organization Outer Dynein Arm Assembly Inner Dynein Arm Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Axonemal Dynein Complex Assembly Determination Of Digestive Tract Left/right Asymmetry
Pathways		Acyl chain remodelling of PE
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: APP DNAAF19 GPANK1 HGS TLX3 UBQLN1 ZIC1	17 interacting genes: CENPN GRIPAP1 HGS MEOX1 MEOX2 PAX6 PICK1 PKN1 PLAAT1 PNMA6A PRKAR1B R3HCC1L RCN3 RUVBL2 SUOX USHBP1 VAC14
Entrez ID		57110	388389
HPRD ID		07577	14200
Ensembl ID		ENSG00000127252	ENSG00000167131
Uniprot IDs		Q9HDD0	Q8IW40
PDB IDs
Enriched GO Terms of Interacting Partners?		Central Nervous System Development Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Adult Locomotory Behavior Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Adult Behavior Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Protein Catabolic Process Lipoprotein Particle Regulation Of Protein Localization To Nucleus Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Regulation Of Transport Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling ESCRT-0 Complex Phagocytic Vesicle Lumen Macroautophagy Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Neuron Differentiation Regulation Of Toll Signaling Pathway Locomotory Behavior Positive Regulation Of Proteolysis Axon Choice Point Recognition	Somite Specification Segment Specification HMG Box Domain Binding Somite Development Regulation Of Vesicle-mediated Transport RNA Polymerase II Core Promoter Sequence-specific DNA Binding
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