LHX9 and IGFN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LHX9	IGFN1
Description		LIM homeobox 9	immunoglobulin like and fibronectin type III domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Cytoplasm Z Disc
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Population Proliferation Male Gonad Development Female Gonad Development Neuron Differentiation Gonad Morphogenesis Negative Regulation Of DNA-templated Transcription Dorsal Spinal Cord Interneuron Anterior Axon Guidance
Pathways		Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549)	Asthma ( 29273806) Height ( 28552196)
Interacting Genes		8 interacting genes: CSNK2A1 CWF19L2 IGFN1 KHK LDB2 SMAD2 SMURF1 UBTFL1	40 interacting genes: ACTMAP BANP BLZF1 COG6 CRX DDAH2 FXR2 GOLGA2 HIVEP1 HOXA1 HOXD3 KCTD9 KIFC3 KRT39 KRTAP6-2 LHX9 LZTS2 MEOX2 MID2 MYOD1 NHLRC4 PIBF1 PNMA1 POF1B POU6F2 PRKAR1B PRR23B SERTAD2 SPAG5 TAX1BP1 TRIM21 TRIM27 TRIM35 TRIM42 TRIP13 TSC1 UBAP2 USP54 ZNF620 ZNF688
Entrez ID		56956	91156
HPRD ID		07299	16812
Ensembl ID		ENSG00000143355	ENSG00000163395
Uniprot IDs		H0YL54 Q9NQ69	Q86VF2
PDB IDs		2DMQ
Enriched GO Terms of Interacting Partners?		Protein Targeting To Vacuole Involved In Autophagy I-SMAD Binding Transforming Growth Factor Beta Receptor Binding R-SMAD Binding Protein Targeting To Vacuole SMAD Binding Establishment Of Protein Localization To Vacuole Ketohexokinase Activity Engulfment Of Target By Autophagosome Positive Regulation Of Cell Growth Protein Localization To Vacuole Protein Kinase CK2 Complex RNA Metabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Vacuolar Transport Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Aggrephagy Response To Glucose Response To Sucrose Response To Carbohydrate Response To Monosaccharide Response To Disaccharide Fructose Binding Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Homomeric SMAD Protein Complex Odontoblast Differentiation Paraxial Mesoderm Morphogenesis Mesoderm Morphogenesis Regulation Of BMP Signaling Pathway SMAD Protein Complex Pericardium Development Trophoblast Cell Migration LIM Domain Binding Activin Receptor Binding RNA Polymerase I General Transcription Initiation Factor Activity Blastocyst Growth Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Heteromeric SMAD Protein Complex Substrate Localization To Autophagosome Post-mRNA Release Spliceosomal Complex Protein Targeting Determination Of Left/right Asymmetry In Lateral Mesoderm RNA Polymerase I Core Promoter Sequence-specific DNA Binding Response To Fructose Embryonic Foregut Morphogenesis RNA Polymerase I Preinitiation Complex Assembly	Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Regulation Of Viral Transcription Protein Binding Golgi Organization Protein Localization To Cytoskeleton Sequence-specific Double-stranded DNA Binding
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