LHX9

Description		LIM homeobox 9
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GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Population Proliferation Male Gonad Development Female Gonad Development Neuron Differentiation Gonad Morphogenesis Negative Regulation Of DNA-templated Transcription Dorsal Spinal Cord Interneuron Anterior Axon Guidance
Pathways		Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549)
Interacting Genes		8 interacting genes: CSNK2A1 CWF19L2 IGFN1 KHK LDB2 SMAD2 SMURF1 UBTFL1
Entrez ID		56956
HPRD ID		07299
Ensembl ID		ENSG00000143355
Uniprot IDs		H0YL54 Q9NQ69
PDB IDs		2DMQ
Enriched GO Terms of Interacting Partners?		Protein Targeting To Vacuole Involved In Autophagy I-SMAD Binding Transforming Growth Factor Beta Receptor Binding R-SMAD Binding Protein Targeting To Vacuole SMAD Binding Establishment Of Protein Localization To Vacuole Ketohexokinase Activity Engulfment Of Target By Autophagosome Positive Regulation Of Cell Growth Protein Localization To Vacuole Protein Kinase CK2 Complex RNA Metabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Vacuolar Transport Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Aggrephagy Response To Glucose Response To Sucrose Response To Carbohydrate Response To Monosaccharide Response To Disaccharide Fructose Binding Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Homomeric SMAD Protein Complex Odontoblast Differentiation Paraxial Mesoderm Morphogenesis Mesoderm Morphogenesis Regulation Of BMP Signaling Pathway SMAD Protein Complex Pericardium Development Trophoblast Cell Migration LIM Domain Binding Activin Receptor Binding RNA Polymerase I General Transcription Initiation Factor Activity Blastocyst Growth Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Heteromeric SMAD Protein Complex Substrate Localization To Autophagosome Post-mRNA Release Spliceosomal Complex Protein Targeting Determination Of Left/right Asymmetry In Lateral Mesoderm RNA Polymerase I Core Promoter Sequence-specific DNA Binding Response To Fructose Embryonic Foregut Morphogenesis RNA Polymerase I Preinitiation Complex Assembly
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