NCLN and NOMO1

Number of citations of the paper that reports this interaction (PubMedID 15257293)
64

Data Source:
BioGRID (cross-linking study, cross-linking study)
HPRD (in vivo, in vitro)

		NCLN	NOMO1
Description		nicalin	NODAL modulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein-containing Complex Multi-pass Translocon Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Multi-pass Translocon Complex
	Molecular Function	Protein Binding Ribosome Binding	Protein Binding Carbohydrate Binding Ribosome Binding
	Biological Process	Determination Of Left/right Asymmetry In Lateral Mesoderm Regulation Of Signal Transduction Regulation Of Protein-containing Complex Assembly Protein Stabilization Regulation Of Protein Complex Stability Multi-pass Transmembrane Protein Insertion Into ER Membrane Negative Regulation Of Nodal Signaling Pathway	Determination Of Left/right Asymmetry In Lateral Mesoderm Multi-pass Transmembrane Protein Insertion Into ER Membrane Negative Regulation Of Nodal Signaling Pathway
Pathways
Drugs			Theophylline
Diseases
GWAS		Asthma ( 31959851) Basophil percentage of white cells ( 32888494) Height ( 31562340) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 29403010 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		3 interacting genes: KRTAP5-9 NOMO1 NOMO3	13 interacting genes: ATF7IP BAG6 DLG4 ECT2 EXOSC10 NCLN SHBG STAT1 TOM1L1 TRIM55 TRIM63 UBQLN4 UPF2
Entrez ID		56926	23420
HPRD ID		07126	11398
Ensembl ID		ENSG00000125912	ENSG00000103512
Uniprot IDs		Q969V3	Q15155
PDB IDs		6W6L 9C7U 9C7V
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nodal Signaling Pathway Regulation Of Nodal Signaling Pathway Multi-pass Transmembrane Protein Insertion Into ER Membrane Multi-pass Translocon Complex Determination Of Left/right Asymmetry In Lateral Mesoderm Negative Regulation Of Activin Receptor Signaling Pathway Regulation Of Activin Receptor Signaling Pathway Protein Insertion Into ER Membrane Protein Insertion Into Membrane Ribosome Binding Determination Of Bilateral Symmetry Determination Of Left/right Symmetry Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Carbohydrate Binding Establishment Of Protein Localization To Membrane Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Pattern Specification Process Localization Within Membrane Endoplasmic Reticulum Membrane Establishment Of Protein Localization Negative Regulation Of Signal Transduction Cellular Localization Negative Regulation Of Cell Communication Endoplasmic Reticulum Negative Regulation Of Signaling Epidermis Development
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