AGPAT3 and NKAPD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AGPAT3	NKAPD1
Description		1-acylglycerol-3-phosphate O-acyltransferase 3	NKAP domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Endomembrane System Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Lysophosphatidic Acid Acyltransferase Activity	Protein Binding Identical Protein Binding
	Biological Process	Lipid Metabolic Process Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process
Pathways		Synthesis of PA COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Estimated glomerular filtration rate in diabetes ( 31451708) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377)
Interacting Genes		19 interacting genes: ABHD16A APP AQP6 BNIP2 CREB3 CREB3L1 FAM133A GOLT1A HSD17B11 HSD17B13 MPP1 NKAPD1 SLC10A1 SLC35H1 SLC71A2 SREK1IP1 TMEM14B TMEM167B TMX2	50 interacting genes: AAMP ACTN1 ACTN2 ACTN3 AGPAT3 AP1M1 AP2M1 ARL6IP4 BEND7 C1orf35 CCDC106 CCNL1 CDCA8 CEP70 COIL CT45A1 DRC4 ELOA2 EXOSC5 FAM133A FRMD6 GOLGA8K H2BC15 HMGXB4 KRCC1 MACROH2A1 MAPK8 MCRS1 MKRN3 MYO15B NKAPL NXF1 PRPF3 PRPF40A RBM39 RNF151 RP9 RPS25 S100B SDCBP SDCBP2 SNRNP25 SREK1IP1 STAC3 TAF1A THAP1 TXLNA U2AF2 ZNF317 ZNF41
Entrez ID		56894	55216
HPRD ID		10637	07695
Ensembl ID		ENSG00000160216	ENSG00000150776
Uniprot IDs		Q9NRZ7	Q6ZUT1
PDB IDs
Enriched GO Terms of Interacting Partners?		Steroid Dehydrogenase Activity Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Positive Regulation Of Monocyte Chemotaxis Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Pseudopodium RNA Splicing Nuclear Speck Focal Adhesion Assembly Microtubule Cytoskeleton Nucleus RNA Processing Muscle Cell Development Cell-substrate Junction Assembly Cell-substrate Junction Organization MRNA Processing Nucleoplasm MRNA Metabolic Process Identical Protein Binding Nucleic Acid Metabolic Process Sarcomere Cortical Actin Cytoskeleton Clathrin Adaptor Complex RNA Metabolic Process Transmembrane Transporter Binding
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