CFAP298 and RPH3A

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		CFAP298	RPH3A
Description		cilia and flagella associated protein 298	rabphilin 3A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Cilium Ciliary Basal Body Cell Projection	Plasma Membrane Synaptic Vesicle Membrane Extrinsic Component Of Membrane Secretory Granule Synaptic Vesicle Membrane Cytoplasmic Vesicle Protein-containing Complex Cell Projection Neuron Projection Dendritic Spine Synapse Postsynaptic Membrane Extrinsic Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Zinc Ion Binding Lipid Binding Selenium Binding Small GTPase Binding Phosphate Ion Binding Protein-containing Complex Binding Metal Ion Binding Inositol 1,4,5 Trisphosphate Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Regulation Of Cilium Movement Cilium Assembly	Intracellular Protein Transport Protein Transport Synaptic Vesicle Priming Positive Regulation Of Calcium Ion-dependent Exocytosis Spontaneous Neurotransmitter Secretion Calcium-dependent Activation Of Synaptic Vesicle Fusion
Pathways
Drugs
Diseases
GWAS			Alcohol consumption (max-drinks) ( 29460428) Apolipoprotein B levels ( 32203549) Body mass index ( 26426971) Chloride levels ( 29403010) Coronary artery disease ( 32469254) Epilepsy ( 33913524) LDL cholesterol levels ( 32203549) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Low density lipoprotein cholesterol levels ( 29403010 32154731) Low HDL-cholesterol levels ( 31006500) Platelet count ( 22139419) Serum uric acid levels ( 32514006) Spleen volume ( 34128465) Urate levels ( 31578528)
Interacting Genes		21 interacting genes: APP COPS5 ERBB2 EWSR1 FMN2 GMCL1 KPNA4 MAPK6 NCOA2 PAX6 PTGER4 RANBP9 RFX5 RPH3A SNRNP70 SPTBN4 TAF1 TRPS1 UNC13B ZNF521 ZNF624	13 interacting genes: ADD2 CASK CFAP298 GCH1 MYO5A NRXN1 RAB15 RAB27A RAB27B RAB3A RAB3B RAB8A YWHAH
Entrez ID		56683	22895
HPRD ID		10756	15273
Ensembl ID		ENSG00000159079	ENSG00000089169
Uniprot IDs		C9J818 D3DSE6 P57076	Q9Y2J0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macromolecule Metabolic Process Amyloid-beta Complex Positive Regulation Of Metabolic Process Negative Regulation Of Blood Circulation Growth Cone Lamellipodium Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Amylin Binding Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of RNA Metabolic Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Catabolic Process Protein Heterodimerization Activity Regulation Of Metabolic Process Positive Regulation Of Amyloid Precursor Protein Catabolic Process Nucleus Axonogenesis Neuromuscular Junction Development Nucleoplasm Secretion By Cell Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Transcription Coregulator Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Neuron Fate Commitment Establishment Of Organelle Localization Negative Regulation Of Eosinophil Extravasation Positive Regulation Of Androgen Receptor Signaling Pathway Transcription Regulator Inhibitor Activity Positive Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Priming Homologous Chromosome Movement Towards Spindle Pole In Meiosis I Anaphase Chromatin Nuclear Receptor Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Metabolic Process Locomotory Behavior MRNA Transcription By RNA Polymerase II Establishment Of Localization In Cell Regulation Of Amyloid Precursor Protein Catabolic Process Protein-containing Complex Negative Regulation Of Macromolecule Metabolic Process	Myosin V Binding GTPase Activity GTP Binding Regulation Of Exocytosis Exocytosis Secretion By Cell Secretion Intracellular Protein Localization Establishment Of Protein Localization Vesicle GDP Binding Protein Transport Establishment Of Localization In Cell Positive Regulation Of Exocytosis Nucleotide Binding Vesicle Localization Regulation Of Vesicle-mediated Transport Regulation Of Regulated Secretory Pathway Regulation Of Secretion By Cell Regulation Of Secretion Positive Regulation Of Regulated Secretory Pathway Regulation Of Transport Protein Localization To Synapse Vesicle-mediated Transport Organelle Localization G Protein Activity Positive Regulation Of Transport Modulation Of Chemical Synaptic Transmission Protein Localization To Cell Junction Synaptic Vesicle Clustering Vesicle-mediated Transport In Synapse Melanosome Secretory Granule Positive Regulation Of Secretion By Cell Establishment Of Vesicle Localization Trans-Golgi Network Transport Vesicle Positive Regulation Of Secretion Hydrolase Activity GTP-dependent Protein Binding Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Synaptic Vesicle Membrane Synaptic Vesicle Melanosome Localization Pigment Granule Localization Exocytic Vesicle Endosome Multivesicular Body Membrane Late Endosome
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