PSD and RAB40C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		PSD	RAB40C
Description		pleckstrin and Sec7 domain containing	RAB40C, member RAS oncogene family
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Membrane Cleavage Furrow Ruffle Membrane Cell Projection Dendritic Spine Postsynaptic Density, Intracellular Component	Golgi Membrane Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Plasma Membrane Synaptic Vesicle Membrane Cul5-RING Ubiquitin Ligase Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phospholipid Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Signal Transduction Neuron Projection Development Regulation Of ARF Protein Signal Transduction	Exocytosis Cell Migration Protein Ubiquitination Intracellular Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Focal Adhesion Assembly Negative Regulation Of Focal Adhesion Assembly Lipid Droplet Formation
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Adiponectin levels ( 33562295) Disc degeneration (lumbar) ( 22993228) Height ( 18391950) Hip circumference adjusted for BMI ( 34021172) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)
Interacting Genes		5 interacting genes: GLRA2 GMFG GNB5 HEXD RAB40C	3 interacting genes: ANKRD27 PSD TOE1
Entrez ID		5662	57799
HPRD ID		09085	10182
Ensembl ID		ENSG00000059915	ENSG00000197562
Uniprot IDs		A5PKW4 Q86YI3	Q96S21
PDB IDs
Enriched GO Terms of Interacting Partners?		Glycine-gated Chloride Ion Channel Activity Extracellularly Glycine-gated Chloride Channel Activity Actin Filament Debranching GTPase Activator Complex G-protein Gamma-subunit Binding Light Adaption Dark Adaptation Hexosaminidase Activity Transmitter-gated Monoatomic Ion Channel Activity Beta-N-acetylhexosaminidase Activity Excitatory Extracellular Ligand-gated Monoatomic Ion Channel Activity Postsynaptic Membrane Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Glycinergic Synapse Negative Regulation Of Actin Nucleation Negative Regulation Of Voltage-gated Calcium Channel Activity Cell Tip Glycine Binding Cellular Response To Ethanol Actin Filament Severing Arp2/3 Complex Binding Regulation Of Voltage-gated Calcium Channel Activity GTPase Activity Response To Light Intensity Cul5-RING Ubiquitin Ligase Complex Lipid Droplet Formation Negative Regulation Of Focal Adhesion Assembly Cellular Response To Zinc Ion Parallel Fiber To Purkinje Cell Synapse G Protein-coupled Dopamine Receptor Signaling Pathway Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Transporter Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds	Guanyl-nucleotide Exchange Factor Activity Negative Regulation Of SNARE Complex Assembly Negative Regulation Of Vesicle Fusion Tubular Endosome Endosome To Melanosome Transport SnRNA Binding Poly(A)-specific Ribonuclease Activity Regulation Of SNARE Complex Assembly Postsynaptic Density, Intracellular Component Regulation Of ARF Protein Signal Transduction SnRNA 3'-end Processing Early Endosome To Late Endosome Transport Positive Regulation Of Dendrite Morphogenesis Regulation Of Vesicle Fusion SnRNA Processing 3'-5'-RNA Exonuclease Activity
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