PSD

Description		pleckstrin and Sec7 domain containing
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Membrane Cleavage Furrow Ruffle Membrane Cell Projection Dendritic Spine Postsynaptic Density, Intracellular Component
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phospholipid Binding
	Biological Process	Signal Transduction Neuron Projection Development Regulation Of ARF Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: GLRA2 GMFG GNB5 HEXD RAB40C
Entrez ID		5662
HPRD ID		09085
Ensembl ID		ENSG00000059915
Uniprot IDs		A5PKW4 Q86YI3
PDB IDs
Enriched GO Terms of Interacting Partners?		Glycine-gated Chloride Ion Channel Activity Extracellularly Glycine-gated Chloride Channel Activity Actin Filament Debranching GTPase Activator Complex G-protein Gamma-subunit Binding Light Adaption Dark Adaptation Hexosaminidase Activity Transmitter-gated Monoatomic Ion Channel Activity Beta-N-acetylhexosaminidase Activity Excitatory Extracellular Ligand-gated Monoatomic Ion Channel Activity Postsynaptic Membrane Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Glycinergic Synapse Negative Regulation Of Actin Nucleation Negative Regulation Of Voltage-gated Calcium Channel Activity Cell Tip Glycine Binding Cellular Response To Ethanol Actin Filament Severing Arp2/3 Complex Binding Regulation Of Voltage-gated Calcium Channel Activity GTPase Activity Response To Light Intensity Cul5-RING Ubiquitin Ligase Complex Lipid Droplet Formation Negative Regulation Of Focal Adhesion Assembly Cellular Response To Zinc Ion Parallel Fiber To Purkinje Cell Synapse G Protein-coupled Dopamine Receptor Signaling Pathway Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Transporter Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds
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