PTPDC1

Description		protein tyrosine phosphatase domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity
	Biological Process	Cell Projection Organization Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Birth weight ( 31043758) Esophageal adenocarcinoma ( 24121790) Heel bone mineral density ( 30598549) Height ( 20881960) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Parkinson's disease ( 26227905) Type 2 diabetes ( 30054458) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		7 interacting genes: AATK CRKL ERBB3 ERBB4 LMTK2 MID2 TEX11
Entrez ID		138639
HPRD ID		06689
Ensembl ID		ENSG00000158079
Uniprot IDs		A0A087WTF0 A2A3K4 A8K0X7
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuregulin Receptor Activity Cell Death Apoptotic Process Programmed Cell Death Protein Tyrosine Kinase Activity Protein Kinase Activity ERBB2 Signaling Pathway Kinase Activity Animal Organ Development Heart Development Transferase Activity Epidermal Growth Factor Receptor Signaling Pathway Basal Plasma Membrane Neuromuscular Junction ERBB Signaling Pathway Establishment Of Planar Polarity Involved In Nephron Morphogenesis Meiotic Gene Conversion Positive Regulation Of Intracellular Signal Transduction Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of MAPK Cascade Helper T Cell Diapedesis Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Central Nervous System Morphogenesis Myosin VI Binding Gene Conversion Male Gonad Development Neuron Apoptotic Process Chordate Pharynx Development Cerebellar Neuron Development ATP Binding Protein Autophosphorylation Epidermal Growth Factor Receptor Activity Male Meiosis Chromosome Segregation Gonad Development Fertilization Cardiac Muscle Tissue Regeneration Olfactory Bulb Interneuron Differentiation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of MAPK Cascade ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development ERBB2-ERBB4 Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade Parathyroid Gland Development ERBB4-ERBB4 Signaling Pathway Chiasma Assembly Reproductive Structure Development
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