UBAP2 and PLAC8

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		UBAP2	PLAC8
Name		ubiquitin associated protein 2	placenta associated 8
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Chromosome Cytoplasm	Extracellular Region Azurophil Granule Lumen
	Molecular Function	RNA Binding Protein Binding Cadherin Binding	Chromatin Binding
	Biological Process	Regulation Of Gene Expression Hematopoietic Stem Cell Homeostasis	Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Response To Cold Negative Regulation Of Multicellular Organism Growth Defense Response To Bacterium Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis
Pathways		None	Neutrophil degranulation Formation of the nephric duct
GWAS		Adult body size ( 32376654 ) Bipolar disorder ( 20351715 ) Daytime nap ( 33568662 ) Estimated glomerular filtration rate ( 31152163 ) Heel bone mineral density ( 30598549 ) High light scatter reticulocyte count ( 32888494 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Lymphocyte count ( 32888494 ) Mean spheric corpuscular volume ( 32888494 ) Mosquito bite size ( 28199695 ) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892 ) Refractive error ( 32231278 ) Reticulocyte count ( 32888494 ) Reticulocyte fraction of red cells ( 32888494 ) Serum alkaline phosphatase levels ( 33547301 ) Type 2 diabetes ( 30297969 30054458 ) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408 )	QRS interval (sulfonylurea treatment interaction) ( 27958378 )
Novel Interactors		2 novel interactors: GBA2 TMEM8B	None recorded
Interacting Genes		45 interacting genes: ASB13 ATPAF2 BANP C10orf55 CREM DAZAP2 EFHC1 FAM168B FNDC3B FOXH1 HGS IGFN1 ISX ITCH JMJD7 KANK2 KRTAP15-1 LCK MGAT5B NOXA1 NPAS2 NUTF2 OTX1 PLAC8 PLEKHB2 PPP2CA PRSS53 PSMB8 RBPMS RHOXF2 SHC3 SPAG8 SPMIP9 TENT5B TEP1 TFG TLE5 TP53BP1 TRAPPC6A UBC USP7 VENTX VPS37C WRAP53 ZNF34	24 interacting genes: ACTMAP BAG4 COPS5 CYSRT1 FCHO1 KRTAP12-2 KRTAP19-1 KRTAP19-6 LCE1A LCE1C LCE2B LCE5A MEOX2 PLAGL2 PPP3CA RBPMS RHOXF2 SPMIP9 TRAF1 TRIP13 UBAP2 USP54 VAMP5 WWOX
Entrez ID		55833	51316
HPRD ID		06748	06335
Ensembl ID		ENSG00000137073	ENSG00000145287
Uniprot IDs		A0A8C8MQ70 B4DH66 B7Z7P2 Q5T6F2 Q9P0H6	Q9NZF1 X2BQ60
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		P53 Binding Axonemal A Tubule Inner Sheath Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome	Epidermis Development Keratinization Tissue Development