CAND1 and DCUN1D1

Number of citations of the paper that reports this interaction (PMID 21145461)
61

Data Source:
BioGRID (pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)

		CAND1	DCUN1D1
Gene Name		cullin-associated and neddylation-dissociated 1	DCN1, defective in cullin neddylation 1, domain containing 1
Image
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Membrane Cullin-RING Ubiquitin Ligase Complex Extracellular Vesicular Exosome	Ubiquitin Ligase Complex
	Molecular Function	Protein Binding TBP-class Protein Binding	Protein Binding
	Biological Process	SCF Complex Assembly Protein Ubiquitination Cell Differentiation Negative Regulation Of Catalytic Activity Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly	Biological_process
Pathways
Drugs
Diseases
GWAS		Hippocampal atrophy ( 19668339)
Protein-Protein Interactions		10 interactors: CNOT3 CUL1 CUL2 CUL3 CUL4A CUL4B DCUN1D1 RBX1 SRPK2 UBE2M	21 interactors: ARRDC3 AURKB CALM1 CAND1 CUL2 CUL3 CUL4A CUL4B DAZAP2 LAPTM5 LZTS2 NEDD4 NEDD8 RHOA RNF11 SMAD2 TP53BP2 TRIM39 TRIM54 UBE2F VPS37B
Entrez ID		55832	54165
HPRD ID		06983	12067
Ensembl ID
Uniprot IDs		Q86VP6	C9JVE2 Q96GG9
PDB IDs		1U6G 4A0C	3TDU 3TDZ
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Monoubiquitination Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cell Cycle Arrest G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway Catabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Cellular Protein Modification Process Protein Neddylation Apoptotic Signaling Pathway Proteolysis Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Cellular Protein Metabolic Process Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Cell Cycle G1/S Phase Transition Trophectodermal Cell Differentiation Viral Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Cell Cycle Mitotic Cell Cycle Process Blastocyst Formation Mitotic Cell Cycle Regulation Of Cell Proliferation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Protein Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Neuron Apoptotic Process Nuclear Speck Organization Regulation Of Nucleotide-excision Repair Positive Regulation Of Neuron Death	Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Catabolic Process Regulation Of Cytokinesis Cellular Macromolecule Catabolic Process Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Process Cellular Response To Light Stimulus Cellular Protein Modification Process Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Positive Regulation Of Cytokinesis Cellular Response To Radiation Catabolic Process Protein Monoubiquitination Cell Cycle Cleavage Furrow Formation Positive Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Process Positive Regulation Of Cell Cycle Phase Transition Intrinsic Apoptotic Signaling Pathway Proteolysis Cellular Response To UV Protein Neddylation Mitotic Cell Cycle Regulation Of Signal Transduction Response To Radiation Negative Regulation Of Cell Cycle Spindle Midzone Assembly Cellular Protein Metabolic Process Spindle Assembly Regulation Of Cell Division Regulation Of Signaling Developmental Process Viral Process Protein Metabolic Process Cytokinesis Mitotic Nuclear Division Positive Regulation Of Mitotic Cell Cycle Mitotic Spindle Assembly Protein Complex Assembly Cell Cycle Process Positive Regulation Of Cell Division Response To Light Stimulus Spindle Organization Cellular Protein Complex Assembly
Tagcloud ?		cdk2 character diagnomx diagnosticpathology differentially dysregulated enrichment eu failure hope http hub omnibus ontology pls powerful preventive rela representation shed signatures slide slides smurf1 squares srsf1 virtual www ywhae	achilles adapter adapters amplicons amplifications amplified atlas backgrounds bioinformatics datasets driver druggable emphasis fgfr frs2 gistic2 grb7 hedgehog kras narrowed nsd3 pik3ca projects putative referencing shrna spanning tailoring tcga
Tagcloud (Difference) ?		cdk2 character diagnomx diagnosticpathology differentially dysregulated enrichment eu failure hope http hub omnibus ontology pls powerful preventive rela representation shed signatures slide slides smurf1 squares srsf1 virtual www ywhae	achilles adapter adapters amplicons amplifications amplified atlas backgrounds bioinformatics datasets driver druggable emphasis fgfr frs2 gistic2 grb7 hedgehog kras narrowed nsd3 pik3ca projects putative referencing shrna spanning tailoring tcga
Tagcloud (Intersection) ?