ZBTB8OS and PRKCH

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		ZBTB8OS	PRKCH
Gene Name		zinc finger and BTB domain containing 8 opposite strand	protein kinase C, eta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome TRNA-splicing Ligase Complex	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Extracellular Vesicular Exosome
	Molecular Function	Metal Ion Binding	Protein Kinase C Activity Calcium-independent Protein Kinase C Activity ATP Binding Ral GTPase Binding Enzyme Binding Metal Ion Binding
	Biological Process	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation	Protein Phosphorylation Signal Transduction Blood Coagulation Positive Regulation Of Macrophage Derived Foam Cell Differentiation Platelet Activation Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Protein Kinase C Signaling Regulation Of Tight Junction Assembly
Pathways			G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK G alpha (z) signalling events Platelet activation, signaling and aggregation Effects of PIP2 hydrolysis
Drugs
Diseases
GWAS			Obesity (early onset extreme) ( 23563609) Reading and spelling ( 23738518) Rheumatoid arthritis ( 22446963) Word reading ( 23738518)
Protein-Protein Interactions		1 interactors: PRKCH	13 interactors: BANP CDK2 FYN GSK3A ITGB2 NFE2L2 NUMB PARD6A PPP1R14A PRKD1 PTPN11 SRC ZBTB8OS
Entrez ID		339487	5583
HPRD ID		12470	05669
Ensembl ID			ENSG00000027075
Uniprot IDs		A8K0B5 Q8IWT0	P24723
PDB IDs			2FK9 3TXO
Enriched GO Terms of Interacting Partners?		Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Keratinocyte Differentiation Regulation Of Tight Junction Assembly Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Glial Cell Proliferation Regulation Of B Cell Receptor Signaling Pathway Regulation Of Keratinocyte Differentiation Protein Kinase C Signaling Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Epidermis Development Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Gliogenesis Regulation Of Epidermis Development Regulation Of Cell Junction Assembly Positive Regulation Of Epithelial Cell Differentiation Regulation Of Gliogenesis Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Epithelial Cell Differentiation Platelet Activation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Cellular Response To Growth Factor Stimulus Response To Growth Factor Integrin-mediated Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Blood Coagulation Innate Immune Response Hemostasis Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Immune Response-regulating Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Protein Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Leukocyte Migration Neurotrophin Signaling Pathway T Cell Costimulation Regulation Of Body Fluid Levels Chemotaxis Fc Receptor Signaling Pathway Wound Healing Regulation Of Cellular Response To Insulin Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus Cellular Response To Peptide Hormone Stimulus Response To Platelet-derived Growth Factor Negative Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ephrin Receptor Signaling Pathway Cellular Response To Peptide Cellular Response To Organic Substance Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Wounding Activated T Cell Proliferation Cell Proliferation Locomotion Immune Response Regulation Of Phosphorylation Defense Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Signal Transduction Axon Guidance Cell Migration Phosphatidylinositol-mediated Signaling Response To Oxidative Stress Cell Surface Receptor Signaling Pathway Regulation Of Immune Response Movement Of Cell Or Subcellular Component Regulation Of Phosphorus Metabolic Process Cell Motility
Tagcloud ?		arch archaea archease asw c14orf166 c22orf28 c2orf49 cgi cooperation d10wsu52e ddx1 dead eukaryotes faap fam98b guanylate helicase hspc117 implies interplay ligase ligases ligation multimeric orthologous rtcb splicing trna trnas	adjust adora2a avp cart cecal clp gng7 intramuscular ku myh7 oxt pde1b pdyn preconditioning prkcd puncture ratref reproduced rgs9 rxrg s100a8 sepsis six3 slc17a6 slco1a5 sostdc1 tac1 ttr ulinastatin
Tagcloud (Difference) ?		arch archaea archease asw c14orf166 c22orf28 c2orf49 cgi cooperation d10wsu52e ddx1 dead eukaryotes faap fam98b guanylate helicase hspc117 implies interplay ligase ligases ligation multimeric orthologous rtcb splicing trna trnas	adjust adora2a avp cart cecal clp gng7 intramuscular ku myh7 oxt pde1b pdyn preconditioning prkcd puncture ratref reproduced rgs9 rxrg s100a8 sepsis six3 slc17a6 slco1a5 sostdc1 tac1 ttr ulinastatin
Tagcloud (Intersection) ?