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SAYSD1 and UFM1
Number of citations of the paper that reports this interaction (PubMedID
36848233
)
56
Data Source:
BioGRID
(pull down)
SAYSD1
UFM1
Description
SAYSVFN motif domain containing 1
ubiquitin fold modifier 1
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Nucleus
Cytoplasm
Endoplasmic Reticulum
Molecular Function
UFM1-modified Protein Reader Activity
Protein Binding
Biological Process
Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins
Rescue Of Stalled Ribosome
Brain Development
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Response To Endoplasmic Reticulum Stress
Negative Regulation Of Protein Import Into Nucleus
Negative Regulation Of Apoptotic Process
Reticulophagy
Protein Ufmylation
Protein K69-linked Ufmylation
Pathways
Drugs
Diseases
GWAS
Body mass index and diastolic blood pressure (bivariate analysis) (
33539483
)
Body mass index and systolic blood pressure (bivariate analysis) (
33539483
)
Coronary artery disease (
32469254
)
Diastolic blood pressure (
27841878
)
Protein C levels (
28082259
)
Aggressiveness in attention deficit hyperactivity disorder (
27021288
)
Body mass index and diastolic blood pressure (bivariate analysis) (
33539483
)
Low vWF levels (
26486471
)
Schizophrenia (
30285260
33169155
)
Interacting Genes
5 interacting genes:
HSPA8
RPL26
RPL5
RPS2
UFM1
16 interacting genes:
ARHGDIA
ARHGDIB
DIABLO
GSK3B
INCA1
KCTD21
RPS6KA6
SAYSD1
TSC22D2
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E3
UBE2W
Entrez ID
55776
51569
HPRD ID
12892
15644
Ensembl ID
ENSG00000112167
ENSG00000120686
Uniprot IDs
Q9NPB0
P61960
PDB IDs
1WXS
5HKH
5IA7
5IA8
5IAA
5L95
6H77
7W3N
8BZR
8OHD
8OJ0
8OJ5
8QFC
Enriched GO Terms of Interacting Partners
?
Ribonucleoprotein Complex
Cytosolic Ribosome
Cytoplasmic Translation
Structural Constituent Of Ribosome
Ribosome
MRNA 5'-UTR Binding
Regulation Of Ubiquitin-protein Transferase Activity
Nucleolus
Ribosomal Large Subunit Biogenesis
Translation
Cytosolic Large Ribosomal Subunit
Focal Adhesion
Protein Metabolic Process
Chaperone-mediated Autophagy Translocation Complex Disassembly
RNA Binding
Regulation Of Translation Involved In Cellular Response To UV
Regulation Of Signal Transduction By P53 Class Mediator
Lumenal Side Of Lysosomal Membrane
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Translation
Regulation Of Protein Import
Extracellular Exosome
Positive Regulation Of Protein Metabolic Process
Ribonucleoprotein Complex Biogenesis
Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy
RNA Processing
C3HC4-type RING Finger Domain Binding
Clathrin Coat Disassembly
Regulation Of Protein Ubiquitination
RRNA Processing
Negative Regulation Of Protein Neddylation
Protein K69-linked Ufmylation
ATP-dependent Protein Disaggregase Activity
Vesicle Uncoating
Macromolecule Metabolic Process
Regulation Of Post-translational Protein Modification
RRNA Metabolic Process
Chaperone-mediated Autophagy
Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Negative Regulation Of Ubiquitin Protein Ligase Activity
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Protein Ufmylation
Autophagy
Ubiquitin Protein Ligase Binding
5S RRNA Binding
Cadherin Binding
Negative Regulation Of Ubiquitin-protein Transferase Activity
Ubiquitin Ligase Inhibitor Activity
Ubiquitin Conjugating Enzyme Activity
Protein K48-linked Ubiquitination
Ubiquitin-protein Transferase Activity
Proteolysis Involved In Protein Catabolic Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Ubiquitination
Protein K11-linked Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Monoubiquitination
Proteolysis
Post-translational Protein Modification
ATP Binding
TOR Signaling
Macromolecule Catabolic Process
Rho GDP-dissociation Inhibitor Activity
Protein Modification Process
Transferase Activity
Nucleotide Binding
TORC1 Signaling
Protein Metabolic Process
Negative Regulation Of TOR Signaling
Catabolic Process
Protein K6-linked Ubiquitination
Regulation Of TOR Signaling
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins
Regulation Of Signal Transduction
Intracellular Signal Transduction
Proteasomal Protein Catabolic Process
Regulation Of Microtubule Anchoring At Centrosome
Negative Regulation Of Signal Transduction
Rho Protein Signal Transduction
Regulation Of Cell Communication
Regulation Of Signaling
Superior Temporal Gyrus Development
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of Signaling
Negative Regulation Of Mesenchymal Stem Cell Differentiation
Negative Regulation Of Glycogen (starch) Synthase Activity
Negative Regulation Of Cell Communication
Negative Regulation Of TORC1 Signaling
Negative Regulation Of BMP Signaling Pathway
Negative Regulation Of Embryonic Development
Protein Autoubiquitination
Protein Catabolic Process
Protein K63-linked Ubiquitination
Cellular Response To Redox State
Negative Regulation Of Mesoderm Development
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Tagcloud (Intersection)
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