UFM1 and ARHGDIB

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		UFM1	ARHGDIB
Gene Name		ubiquitin-fold modifier 1	Rho GDP dissociation inhibitor (GDI) beta
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Extracellular Vesicular Exosome	Cytoplasm Cytosol Cytoskeleton Cytoplasmic Membrane-bounded Vesicle Extracellular Vesicular Exosome
	Molecular Function		Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity
	Biological Process	Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Protein Ufmylation Protein Polyufmylation	Movement Of Cell Or Subcellular Component Immune Response Negative Regulation Of Cell Adhesion Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Multicellular Organismal Development Actin Cytoskeleton Organization Positive Regulation Of GTPase Activity Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ARHGDIA ARHGDIB DIABLO GSK3B RPS6KA6 UBA5 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2W UFC1	11 interactors: APP CASP3 CDC42 EZR RAC1 RAC2 RAC3 RHOA RHOH UFM1 VAV1
Entrez ID		51569	397
HPRD ID		15644	04162
Ensembl ID		ENSG00000120686	ENSG00000111348
Uniprot IDs		P61960	P52566
PDB IDs		1WXS	1DS6
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Protein Ubiquitination Cellular Response To Stress Cellular Protein Modification Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Metabolic Process Cellular Protein Metabolic Process Protein Monoubiquitination Protein Polyufmylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Protein Ufmylation Regulation Of DNA-templated Transcription In Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Cellular Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Protein Catabolic Process Positive Regulation Of Proteolysis Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Response To Stress Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Activation Of Innate Immune Response Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Response To Endoplasmic Reticulum Stress Response To Stimulus Immune Response-regulating Signaling Pathway Positive Regulation Of Catalytic Activity Positive Regulation Of Innate Immune Response Protein K63-linked Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint	Chemotaxis Small GTPase Mediated Signal Transduction Neuron Differentiation Response To Wounding Cell Morphogenesis Involved In Differentiation Axon Guidance Regulation Of Small GTPase Mediated Signal Transduction Blood Coagulation Hemostasis Platelet Activation Neuron Projection Development Generation Of Neurons Neuron Development Axonogenesis Axon Development Neurogenesis Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Morphogenesis Wound Healing Actin Cytoskeleton Organization Cell Projection Assembly Regulation Of Cell Adhesion Neuron Projection Morphogenesis Cell Development Actin Filament-based Process Cell Projection Organization Regulation Of Signal Transduction Intracellular Signal Transduction Cell Adhesion Cell Activation Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Locomotion Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Signaling Positive Regulation Of Cell Morphogenesis Involved In Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Nervous System Development Movement Of Cell Or Subcellular Component Cell Differentiation Regulation Of Cell Morphogenesis Regulation Of Cell-substrate Adhesion Anatomical Structure Morphogenesis Neurotrophin TRK Receptor Signaling Pathway Single Organismal Cell-cell Adhesion Neurotrophin Signaling Pathway Regulation Of Intracellular Signal Transduction Epithelium Development
Tagcloud ?		17beta abrogated activating asc1 bound coactivator displaced e1 e2 eralpha establish estradiol knockdown largely maintains nonufmylated polyufmylation prevented promoted promoters promoting protease screened src1 tamoxifen transactivation uba5 ufmylation ufsp2	address affecting autonomous bcl3 concomitant deregulated dissociation erbb2 gdp intrinsic lungs malignancy mammary metalloprotease mmtv modifying motility neu nme1 nme2 nme3 oncogene oncogenic proto rescued solid timp1 timp2 turnover
Tagcloud (Difference) ?		17beta abrogated activating asc1 bound coactivator displaced e1 e2 eralpha establish estradiol knockdown largely maintains nonufmylated polyufmylation prevented promoted promoters promoting protease screened src1 tamoxifen transactivation uba5 ufmylation ufsp2	address affecting autonomous bcl3 concomitant deregulated dissociation erbb2 gdp intrinsic lungs malignancy mammary metalloprotease mmtv modifying motility neu nme1 nme2 nme3 oncogene oncogenic proto rescued solid timp1 timp2 turnover
Tagcloud (Intersection) ?