SAYSD1

Description		SAYSVFN motif domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	UFM1-modified Protein Reader Activity
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Rescue Of Stalled Ribosome
Pathways
Drugs
Diseases
GWAS		Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483) Body mass index and systolic blood pressure (bivariate analysis) ( 33539483) Coronary artery disease ( 32469254) Diastolic blood pressure ( 27841878) Protein C levels ( 28082259)
Interacting Genes		5 interacting genes: HSPA8 RPL26 RPL5 RPS2 UFM1
Entrez ID		55776
HPRD ID		12892
Ensembl ID		ENSG00000112167
Uniprot IDs		Q9NPB0
PDB IDs
Enriched GO Terms of Interacting Partners?		Ribonucleoprotein Complex Cytosolic Ribosome Cytoplasmic Translation Structural Constituent Of Ribosome Ribosome MRNA 5'-UTR Binding Regulation Of Ubiquitin-protein Transferase Activity Nucleolus Ribosomal Large Subunit Biogenesis Translation Cytosolic Large Ribosomal Subunit Focal Adhesion Protein Metabolic Process Chaperone-mediated Autophagy Translocation Complex Disassembly RNA Binding Regulation Of Translation Involved In Cellular Response To UV Regulation Of Signal Transduction By P53 Class Mediator Lumenal Side Of Lysosomal Membrane Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Intracellular Signal Transduction Positive Regulation Of Translation Regulation Of Protein Import Extracellular Exosome Positive Regulation Of Protein Metabolic Process Ribonucleoprotein Complex Biogenesis Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy RNA Processing C3HC4-type RING Finger Domain Binding Clathrin Coat Disassembly Regulation Of Protein Ubiquitination RRNA Processing Negative Regulation Of Protein Neddylation Protein K69-linked Ufmylation ATP-dependent Protein Disaggregase Activity Vesicle Uncoating Macromolecule Metabolic Process Regulation Of Post-translational Protein Modification RRNA Metabolic Process Chaperone-mediated Autophagy Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Ufmylation Autophagy Ubiquitin Protein Ligase Binding 5S RRNA Binding Cadherin Binding Negative Regulation Of Ubiquitin-protein Transferase Activity Ubiquitin Ligase Inhibitor Activity
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