RAB33A and LRP2BP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RAB33A	LRP2BP
Description		RAB33A, member RAS oncogene family	LRP2 binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Golgi Apparatus Plasma Membrane Membrane	Cytoplasm
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding	Protein Binding
	Biological Process	Autophagosome Assembly Antigen Processing And Presentation Rab Protein Signal Transduction
Pathways		TBC/RABGAPs RAB geranylgeranylation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Height ( 31562340)	Systemic sclerosis ( 33069728)
Interacting Genes		15 interacting genes: ARL6IP1 ATG16L1 ATG16L2 CCDC136 KRT31 KRT34 LNX1 LRP2BP PSMF1 RABAC1 RTN3 RTN4 RUFY2 RUFY3 SIAH1	25 interacting genes: ADGRB2 C1orf50 CCDC24 CDKL3 CDKN1A COPS3 DTX2 FAAP20 FAM90A1 GAS2L2 GEM GPKOW GSTP1 HOXC8 LENG1 LRP2 P4HA3 PICK1 RAB33A RBM4 SCNM1 SMARCC1 SNW1 TSC22D4 ZNF587
Entrez ID		9363	55805
HPRD ID		02272	10911
Ensembl ID		ENSG00000134594	ENSG00000109771
Uniprot IDs		Q14088	Q9P2M1
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Tubular Network Formation Endoplasmic Reticulum Tubular Network Membrane Organization Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Organization Negative Stranded Viral RNA Replication Atg12-Atg5-Atg16 Complex Viral RNA Genome Replication Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Phagophore Assembly Site Membrane Viral Genome Replication Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Organelle Organization GTPase Binding Supramolecular Fiber Organization Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Amyloid-beta Formation Negative Regulation Of Axonogenesis Vacuole-isolation Membrane Contact Site Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Structural Constituent Of Skin Epidermis Nervous System Development Positive Regulation Of Retrograde Axon Cargo Transport C-terminal Protein Lipidation Intermediate Filament Organization Cell Differentiation Regulation Of Amide Metabolic Process Regulation Of Axon Extension Autophagosome Regulation Of Developmental Growth Positive Regulation Of Protein Localization To Endoplasmic Reticulum Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Autophagosome Assembly Negative Regulation Of Developmental Growth Positive Regulation Of L-glutamate Import Across Plasma Membrane Negative Regulation Of Dendrite Extension Cell Migration Involved In Vasculogenesis Autophagosome Organization Regulation Of Endoplasmic Reticulum Tubular Network Organization Regulation Of Branching Morphogenesis Of A Nerve Intracellular Sphingolipid Homeostasis Central Nervous System Vasculogenesis Endoplasmic Reticulum Tubular Network Membrane Regulation Of Cell Growth Negative Regulation Of Neuron Projection Development	Cellular Response To Cell-matrix Adhesion
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