LRRC59 and TMEM97

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LRRC59	TMEM97
Description		leucine rich repeat containing 59	transmembrane protein 97
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondrial Nucleoid	Nucleus Lysosome Endoplasmic Reticulum Rough Endoplasmic Reticulum Plasma Membrane Membrane Rough Endoplasmic Reticulum Membrane Nuclear Membrane
	Molecular Function	RNA Binding Protein Binding Cadherin Binding	Protein Binding Oxysterol Binding Cholesterol Binding
	Biological Process	Intracellular Signal Transduction	Regulation Of Cell Growth Regulation Of Intracellular Lipid Transport Regulation Of Intracellular Cholesterol Transport Cholesterol Homeostasis Positive Regulation Of Wound Healing Positive Regulation Of Lipoprotein Transport
Pathways
Drugs
Diseases
GWAS			Advanced age-related macular degeneration ( 26691988) Osteoprotegerin levels ( 25080503)
Interacting Genes		19 interacting genes: AGTRAP AQP1 CMTM3 CMTM5 CNIH1 CSNK2A1 EBP EDDM3B MTNR1A NDRG4 PLPP4 SGO1 SNORC TMBIM6 TMEM222 TMEM60 TMEM97 TRAM1L1 TSPO2	66 interacting genes: APP AQP12B AQP2 AQP6 ARL13B ASZ1 ATP6AP2 BCL2L13 BIK CD53 CD74 CD79A CGRRF1 CLDN7 CLSTN3 CPLX4 EBP ERGIC3 FAM209A FFAR2 FKBP7 FRMD3 FXYD3 GJA8 GJB3 GJB5 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LEUTX LHFPL5 LIME1 LRRC59 MFF MRM1 MTIF3 MUC1 NDUFAF1 NDUFAF2 NEMP1 PDCD1LG2 PDZK1IP1 PLP1 PSCA REEP1 RHCG RNF170 SAR1A SGPL1 SLC10A1 SLC14A1 SLC14A2 SLC18A1 SLC35H1 SPINT1 SSMEM1 TMEM106C TMEM14B TMEM45B TMEM52B TMEM79 TMX2 VSIR
Entrez ID		55379	27346
HPRD ID		15181	14343
Ensembl ID		ENSG00000108829	ENSG00000109084
Uniprot IDs		Q96AG4	Q5BJF2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Nuclear Membrane Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Endoplasmic Reticulum Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cholesterol-5,6-oxide Hydrolase Activity Blastocyst Hatching 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity	Membrane Water Transport One-carbon Compound Transport Fluid Transport Protein Binding Water Channel Activity Endoplasmic Reticulum Membrane Connexin Complex Endoplasmic Reticulum Gap Junction Channel Activity Plasma Membrane B Cell Receptor Complex Water Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Mitochondrial Membrane Gap Junction Urea Transmembrane Transporter Activity Transmembrane Transport
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