PPP5C and SIM2

  • Number of citations of the paper that reports this interaction (PubMedID 35914814)
  • 83
  • Data Source:
  • BioGRID (two hybrid)

PPP5C

SIM2

Description protein phosphatase 5 catalytic subunit SIM bHLH transcription factor 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Basophil percentage of white cells ( 27863252)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Eosinophil count ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Hemoglobin ( 32888494)
  • Lymphocyte count ( 32888494)
  • Neuroticism ( 29255261)
  • Response to antidepressants in depression ( 29998114)
  • Triglyceride levels ( 32203549)
Interacting Genes 30 interacting genes: APP BRWD1 CDC16 CDC27 CDC37 CDK20 CEBPA CHORDC1 CPNE1 CPNE2 CPNE4 CRY2 CSE1L CSNK1D DISC1 EGFR ESR2 GNA12 GNA13 HSP90AA1 HTR2A HUWE1 MAP3K5 MAP3K7 MAPT OGT PPP2R1A PPP2R3A SIM2 VHL 9 interacting genes: ADD3 ARNT EPS15L1 MAGED1 PAX6 PPP5C PREX1 PRKN PTGES3
Entrez ID 5536 6493
HPRD ID 02805 02935
Ensembl ID ENSG00000011485 ENSG00000159263
Uniprot IDs P53041 Q14190
PDB IDs 1A17 1S95 1WAO 2BUG 3H60 3H61 3H62 3H63 3H64 3H66 3H67 3H68 3H69 4ZVZ 4ZX2 5HPE 5UI1 5WG8 7ZR5 7ZR6 8GAE 8GFT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?