SIM2

Gene Name		single-minded family bHLH transcription factor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Signal Transducer Activity Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Signal Transduction Nervous System Development Embryonic Pattern Specification Cell Differentiation Lung Development
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: ARNT ARNT2 PARK2
Entrez ID		6493
HPRD ID		02935
Ensembl ID		ENSG00000159263
Uniprot IDs		Q14190
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Regulation Of Carbohydrate Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Linear Polyubiquitination Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Manganese Ion Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Negative Regulation Of Mitochondrial Fusion Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Fusion Negative Regulation Of Glucokinase Activity Neuron Cellular Homeostasis Positive Regulation Of Oxidative Stress-induced Cell Death Protein K6-linked Ubiquitination Transcription, DNA-templated Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Neuron Death RNA Biosynthetic Process Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrion Degradation Positive Regulation Of Cellular Metabolic Process Dopamine Transport In Utero Embryonic Development Positive Regulation Of Hormone Biosynthetic Process Aggresome Assembly MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Glycolytic Process Regulation Of Mitochondrial Fission Neurotransmitter Uptake Norepinephrine Metabolic Process Positive Regulation Of Protein Sumoylation Negative Regulation Of Actin Filament Bundle Assembly Synaptic Transmission, Dopaminergic MRNA Transcription Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Zinc Ion Homeostasis Negative Regulation Of Release Of Cytochrome C From Mitochondria
Tagcloud ?		clathrin cns colocalized confocal critical deficits ds elusive endocytosis exacerbates exact hybrid immunoprecipitation interacted laser learning mad2b mediate microscopy minded mitotic nervous neurons overexpression pathophysiological scanning thereby thought transferrin