ANKRD10 and FOXI1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		ANKRD10	FOXI1
Name		ankyrin repeat domain 10	forkhead box I1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Chromatin Nucleus Nucleolus
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding DNA Binding, Bending Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	None	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Embryo Development Ending In Birth Or Egg Hatching Cell Differentiation Inner Ear Morphogenesis Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Diseases		None	Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS		Apolipoprotein A1 levels ( 32203549 ) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223 ) Refractive error ( 32231278 )	Acne (severe) ( 24927181 ) Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065 )
Interacting Genes		16 interacting genes: APPBP2 ATG9A CSTF2 FAM222B FOXI1 GIGYF1 OTX1 PEF1 PITX1 POGZ POU6F2 SHC3 SNRPC TLX3 TRIP13 ZIC1	27 interacting genes: ANKRD10 APP ARSA ATP23 BATF2 CSTF2T DTX2 FAM168B FAM83A HGS HSF4 JMJD7 KRTAP19-1 KRTAP19-7 MAGED1 MLLT10 NFKBID PIN1 RAMAC TEKT5 TENT5B UFSP1 USP54 VPS37C WDR25 WWOX YAP1
Entrez ID		55608	2299
HPRD ID		12455	03057
Ensembl ID		ENSG00000088448	ENSG00000168269
Uniprot IDs		Q9NXR5	E0XEN6 Q12951
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		DNA-binding Transcription Factor Activity Inner Ear Morphogenesis Central Nervous System Development Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Embryonic Morphogenesis	None