BRIX1 and CD48

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BRIX1	CD48
Gene Name		BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)	CD48 molecule
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus	Plasma Membrane Integral Component Of Plasma Membrane Membrane Anchored Component Of Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Poly(A) RNA Binding	Receptor Activity Protein Binding
	Biological Process	Ribosomal Large Subunit Assembly	Defense Response Blood Coagulation Leukocyte Migration
Pathways			Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		5 interactors: CD48 GSK3B SETDB1 UBA2 UNC119	10 interactors: BRIX1 CD2 CD244 CD247 EEF1D FYN GNAI3 IL18R1 IL18RAP LCK
Entrez ID		55299	962
HPRD ID		16563	00177
Ensembl ID			ENSG00000117091
Uniprot IDs		Q8TDN6	P09326
PDB IDs			2EDO
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Type B Pancreatic Cell Development SMT3-dependent Protein Catabolic Process Negative Regulation Of Caveolin-mediated Endocytosis Superior Temporal Gyrus Development Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Cytokinesis, Completion Of Separation Peptidyl-amino Acid Modification Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Cellular Response To Interleukin-3 Peptidyl-lysine Modification Regulation Of Neuron Maturation Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Glycogen (starch) Synthase Activity Mitotic Cytokinetic Process Protein Localization To Microtubule Negative Regulation Of Dendrite Morphogenesis Negative Regulation Of NFAT Protein Import Into Nucleus Histone H3-K9 Trimethylation ER Overload Response Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Muscle Hypertrophy Regulation Of Glycogen (starch) Synthase Activity Regulation Of Clathrin-mediated Endocytosis Positive Regulation Of Catalytic Activity Negative Regulation Of Transport Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Protein Export From Nucleus Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Dendrite Development Cell Separation After Cytokinesis Lipoprotein Transport Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Cellular Ketone Metabolic Process Regulation Of DNA Methylation Histone H3-K9 Methylation Inner Cell Mass Cell Proliferation Myoblast Fusion Protein Localization To Cytoskeleton Peptidyl-lysine Trimethylation Protein Sumoylation Blastocyst Growth Regulation Of Gene Expression By Genetic Imprinting Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Response To Lithium Ion Regulation Of Cellular Response To Heat	Regulation Of Defense Response To Virus By Virus Blood Coagulation Hemostasis Leukocyte Migration Regulation Of Body Fluid Levels Wound Healing T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation T Cell Costimulation Cell Activation Regulation Of T Cell Activation Regulation Of Defense Response To Virus Positive Regulation Of Cell Activation Immune System Process Response To Wounding Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Signal Transduction T Cell Receptor Signaling Pathway Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation Lymphocyte Activation Signaling Antigen Receptor-mediated Signaling Pathway Cell Communication Regulation Of Cell Activation Leukocyte Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Single Organismal Cell-cell Adhesion Cell Surface Receptor Signaling Pathway Platelet Activation Cellular Response To Stimulus Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Adhesion Regulation Of I-kappaB Kinase/NF-kappaB Signaling Immune Response Response To Stress Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Interferon-gamma Production Positive Regulation Of Intracellular Signal Transduction Cell Migration Natural Killer Cell Activation Cell Motility Positive Regulation Of Immune System Process
Tagcloud ?			advance cd150 cdd committed doi effector epo epor erythroblasts erythrocytes erythroid erythropoiesis erythropoietin h2afy2 highlighted hscs immunophenotypically lin macroh2a2 mh2a2 november phospholipase plcgamma1 progenitors publication recapitulated sca1 stat5a tightly
Tagcloud (Difference) ?			advance cd150 cdd committed doi effector epo epor erythroblasts erythrocytes erythroid erythropoiesis erythropoietin h2afy2 highlighted hscs immunophenotypically lin macroh2a2 mh2a2 november phospholipase plcgamma1 progenitors publication recapitulated sca1 stat5a tightly
Tagcloud (Intersection) ?