KLHL26 and ACIN1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		KLHL26	ACIN1
Gene Name		kelch-like family member 26	apoptotic chromatin condensation inducer 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function		Nucleotide Binding Nucleic Acid Binding Protein Binding ATPase Activity Enzyme Binding Poly(A) RNA Binding
	Biological Process		MRNA Processing Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis RNA Splicing Erythrocyte Differentiation Apoptotic Chromosome Condensation Positive Regulation Of Apoptotic Process Positive Regulation Of Monocyte Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways			Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: ACIN1 UBQLN4	11 interactors: ABCF3 AKR1C3 BTBD10 CASP3 CSNK2A1 KLHL26 PAFAH1B2 PCBD1 RNPS1 SRPK2 YWHAG
Entrez ID		55295	22985
HPRD ID		07728	05191
Ensembl ID		ENSG00000167487	ENSG00000100813
Uniprot IDs		Q53HC5	B4DQZ7 Q9UKV3
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Chromosome Condensation Positive Regulation Of Monocyte Differentiation Regulation Of Monocyte Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Apoptotic Nuclear Changes Chromosome Condensation Positive Regulation Of Myeloid Leukocyte Differentiation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of MRNA Splicing, Via Spliceosome Execution Phase Of Apoptosis Positive Regulation Of Myeloid Cell Differentiation Regulation Of MRNA Processing Regulation Of RNA Splicing Erythrocyte Differentiation Regulation Of Myeloid Leukocyte Differentiation Erythrocyte Homeostasis	Regulation Of Cell Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Apoptotic Process Positive Regulation Of Metabolic Process Regulation Of Neuron Death Regulation Of Metabolic Process Positive Regulation Of Neuron Apoptotic Process Regulation Of MRNA Splicing, Via Spliceosome Nuclear Speck Organization Negative Regulation Of Retinoic Acid Biosynthetic Process Catabolic Process Positive Regulation Of Neuron Death Regulation Of MRNA Processing Keratinocyte Differentiation Aromatic Compound Catabolic Process Regulation Of RNA Splicing Regulation Of Testosterone Biosynthetic Process Farnesol Catabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Isoprenoid Metabolic Process Sesquiterpenoid Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Epidermal Cell Differentiation Cellular Response To Jasmonic Acid Stimulus Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Cellular Response To Prostaglandin D Stimulus Intrinsic Apoptotic Signaling Pathway Glial Cell Apoptotic Process Cellular Response To Oxidative Stress Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process System Development Regulation Of Apoptotic DNA Fragmentation Daunorubicin Metabolic Process Doxorubicin Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Kinase Activity Testosterone Biosynthetic Process Negative Regulation Of Catalytic Activity Skin Development Negative Regulation Of Cellular Protein Metabolic Process Tetrahydrobiopterin Biosynthetic Process MRNA Splicing, Via Spliceosome Negative Regulation Of Kinase Activity Positive Regulation Of Cell Proliferation RNA Splicing, Via Transesterification Reactions Regulation Of Neuron Apoptotic Process Lipid Catabolic Process
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