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UEVLD and DTX3
Number of citations of the paper that reports this interaction (PMID
19549727
)
40
Data Source:
BioGRID
(two hybrid)
UEVLD
DTX3
Gene Name
UEV and lactate/malate dehyrogenase domains
deltex 3, E3 ubiquitin ligase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Vesicular Exosome
Cytoplasm
Molecular Function
Molecular_function
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Zinc Ion Binding
Ligase Activity
Biological Process
Cellular Protein Modification Process
Biological_process
Protein Transport
Cellular Carbohydrate Metabolic Process
Oxidation-reduction Process
Notch Signaling Pathway
Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
6 interactors:
DTX3
LRSAM1
RNF114
RNF4
TRAF6
UBC
25 interactors:
DTX1
DTX2
RNF141
RNF38
TRAF4
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2DNL
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2K
UBE2L3
UBE2L6
UBE2V1
UBE2W
UEVLD
USP1
USP2
USP21
XIAP
ZDHHC17
Entrez ID
55293
196403
HPRD ID
15608
16842
Ensembl ID
ENSG00000151116
ENSG00000178498
Uniprot IDs
B4DIA9
Q8IX04
Q8N9I9
PDB IDs
2I6T
3DL2
Enriched GO Terms of Interacting Partners
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Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Protein Autoubiquitination
Cellular Protein Modification Process
Intracellular Receptor Signaling Pathway
Virion Assembly
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Protein K63-linked Ubiquitination
Cellular Protein Metabolic Process
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
I-kappaB Kinase/NF-kappaB Signaling
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Protein Metabolic Process
Toll-like Receptor 4 Signaling Pathway
JNK Cascade
Ubiquitin-dependent Endocytosis
Toll-like Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Protein Catabolic Process
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of NF-kappaB Transcription Factor Activity
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Protein Ubiquitination
Regulation Of Kinetochore Assembly
Antigen Receptor-mediated Signaling Pathway
Notch Signaling Pathway
Activation Of MAPK Activity
Activation Of Innate Immune Response
Regulation Of Centromere Complex Assembly
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Innate Immune Response
Viral Life Cycle
Regulation Of Protein Ubiquitination
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of MAP Kinase Activity
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Cellular Protein Modification Process
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Cellular Protein Metabolic Process
Protein K11-linked Ubiquitination
Protein Metabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Metabolic Process
Proteolysis
ISG15-protein Conjugation
Protein K63-linked Ubiquitination
Regulation Of Proteasomal Protein Catabolic Process
Catabolic Process
Toll-like Receptor 4 Signaling Pathway
Regulation Of Protein Catabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Metabolic Process
Regulation Of Proteolysis
Regulation Of Innate Immune Response
Toll-like Receptor Signaling Pathway
Cellular Response To Stress
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Protein Ubiquitination
Protein Monoubiquitination
Activation Of Innate Immune Response
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Positive Regulation Of Innate Immune Response
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Protein Ubiquitination
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Stimulus
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Cellular Response To DNA Damage Stimulus
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