KLHL15

Description		kelch like family member 15
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Nuclear Protein Quality Control By The Ubiquitin-proteasome System Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways
Drugs
Diseases
GWAS		Prostate-specific antigen levels ( 28139693)
Novel Interacting Genes		1 novel interacting genes: POLA1
Interacting Genes		3 interacting genes: MARCHF6-DT PPP2R2B RBBP8
Entrez ID		80311
HPRD ID		09957
Ensembl ID		ENSG00000174010
Uniprot IDs		Q96M94 V9HWF1
PDB IDs
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Mitotic DNA Replication Initiation Lagging Strand Elongation Alpha DNA Polymerase:primase Complex DNA Synthesis Involved In UV-damage Excision Repair Leading Strand Elongation DNA Replication, Synthesis Of Primer BRCA1-C Complex DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Poly-ADP-D-ribose Binding Regulation Of Protein ADP-ribosylation Single-stranded DNA Endodeoxyribonuclease Activity DNA Strand Elongation Involved In DNA Replication DNA Polymerase Activity DNA Replication Origin Binding Protein Phosphatase Type 2A Complex DNA Strand Resection Involved In Replication Fork Processing DNA Strand Elongation DNA Repair DNA-directed DNA Polymerase Activity DNA Replication Initiation Blastocyst Hatching DNA Double-strand Break Processing
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