ARL8B and DLEU1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		ARL8B	DLEU1
Description		ARF like GTPase 8B	deleted in lymphocytic leukemia 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Endosome Spindle Cytosol Cytoskeleton Membrane Axon Midbody Early Endosome Membrane Late Endosome Membrane Cell Projection Synapse Spindle Midzone Extracellular Exosome Cytolytic Granule Membrane Axon Cytoplasm
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Alpha-tubulin Binding Beta-tubulin Binding
	Biological Process	Plasma Membrane Repair Antigen Processing And Presentation Of Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Following Phagocytosis Chromosome Segregation Anterograde Axonal Transport Protein Transport Endosomal Transport Lysosome Localization Endosomal Vesicle Fusion Early Endosome To Golgi Transport Natural Killer Cell Mediated Cytotoxicity Viral Exocytosis Cell Division Autophagosome-lysosome Fusion Endosome To Lysosome Transport Of Low-density Lipoprotein Particle Phagosome-lysosome Fusion Late Endosome To Lysosome Transport Protein Localization To Early Endosome Calcium Ion Regulated Lysosome Exocytosis
Pathways
Drugs
Diseases
GWAS		Disc degeneration (lumbar) ( 22993228) Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483) Serum alkaline phosphatase levels ( 33547301)	A body shape index ( 34021172) Adiponectin levels ( 26299439) Adiponectin levels (BMI-adjusted) ( 26299439) Aluminium levels ( 26025379) Appendicular lean mass ( 33097823) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Blood urea nitrogen levels ( 31152163) Circulating odd-numbered chain saturated fatty acid levels (C19:0) ( 29738550) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Eosinophil count ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) FEV1 ( 30804560) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 28869591 30598549) Heel bone mineral density x serum urate levels interaction ( 34046847) Height ( 28552196 33713608 31562340 31217584) Hematocrit ( 29403010 32888494) Hemoglobin ( 29403010 32888494) Hip circumference adjusted for BMI ( 28552196 34021172) Hip index ( 34021172) Lipoprotein (a) levels ( 30108283) Low density lipoprotein cholesterol levels ( 32154731) Low hand grip strength (60 years and older) (EWGSOP) ( 33510174) Lung function (FVC) ( 30804560) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 27386562 21833088 31604244) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376) Plasma anti-thyroid peroxidase levels ( 29678681) Platelet distribution width ( 32888494) Primary biliary cholangitis ( 26394269) Prostate-specific antigen levels ( 28139693) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Tumor necrosis factor alpha levels ( 31217265) Type 2 diabetes ( 30297969 30054458 32499647) Urinary albumin-to-creatinine ratio ( 31630189) Urinary magnesium excretion ( 31993563) Waist-hip index ( 34021172) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196 34021172) Weight ( 28552196) White blood cell count ( 32888494)
Interacting Genes		13 interacting genes: AMH APP ATP5MF BTN3A3 CIDEB DLEU1 RAB14 RUFY3 SLC30A8 TGFBR1 TMEM14B TUBB VPS41	20 interacting genes: ABCD4 ABCF3 ARL8B CCDC90B CEP126 COPS6 EEF1A1 EEF1G GDF9 GOPC KAT5 MED31 PSMA1 SETDB1 SHMT1 TLE1 TP53 TUBB4B UBR1 UTP14A
Entrez ID		55207	10301
HPRD ID		12483	16150
Ensembl ID		ENSG00000134108	ENSG00000176124
Uniprot IDs		Q9NVJ2
PDB IDs		2AL7 8JC5 8JCA
Enriched GO Terms of Interacting Partners?		Type II Transforming Growth Factor Beta Receptor Binding Nuclear Envelope Lumen Golgi-associated Vesicle Endosomal Vesicle Fusion Organelle Fusion Signaling Receptor Binding Cytoplasmic Vesicle Positive Regulation Of SMAD Protein Signal Transduction System Development Membrane Raft Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Early Endosome Membrane Lysosome Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Protein Transport
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