ARL8B

Description		ARF like GTPase 8B
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GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Endosome Spindle Cytosol Cytoskeleton Membrane Axon Midbody Early Endosome Membrane Late Endosome Membrane Cell Projection Synapse Spindle Midzone Extracellular Exosome Cytolytic Granule Membrane Axon Cytoplasm
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Alpha-tubulin Binding Beta-tubulin Binding
	Biological Process	Plasma Membrane Repair Antigen Processing And Presentation Of Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Following Phagocytosis Chromosome Segregation Anterograde Axonal Transport Protein Transport Endosomal Transport Lysosome Localization Endosomal Vesicle Fusion Early Endosome To Golgi Transport Natural Killer Cell Mediated Cytotoxicity Viral Exocytosis Cell Division Autophagosome-lysosome Fusion Endosome To Lysosome Transport Of Low-density Lipoprotein Particle Phagosome-lysosome Fusion Late Endosome To Lysosome Transport Protein Localization To Early Endosome Calcium Ion Regulated Lysosome Exocytosis
Pathways
Drugs
Diseases
GWAS		Disc degeneration (lumbar) ( 22993228) Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		13 interacting genes: AMH APP ATP5MF BTN3A3 CIDEB DLEU1 RAB14 RUFY3 SLC30A8 TGFBR1 TMEM14B TUBB VPS41
Entrez ID		55207
HPRD ID		12483
Ensembl ID		ENSG00000134108
Uniprot IDs		Q9NVJ2
PDB IDs		2AL7 8JC5 8JCA
Enriched GO Terms of Interacting Partners?		Type II Transforming Growth Factor Beta Receptor Binding Nuclear Envelope Lumen Golgi-associated Vesicle Endosomal Vesicle Fusion Organelle Fusion Signaling Receptor Binding Cytoplasmic Vesicle Positive Regulation Of SMAD Protein Signal Transduction System Development Membrane Raft Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Early Endosome Membrane Lysosome Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Protein Transport
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