FAIM and ZRANB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAIM	ZRANB1
Description		Fas apoptotic inhibitory molecule	zinc finger RANBP2-type containing 1
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GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Catalytic Activity Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Zinc Ion Binding Hydrolase Activity Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Deubiquitinase Activity
	Biological Process	Apoptotic Process Regulation Of Signal Transduction Negative Regulation Of Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Autophagosome Assembly Proteolysis Cytoskeleton Organization Wnt Signaling Pathway Cell Migration Protein Deubiquitination Regulation Of Cell Morphogenesis Positive Regulation Of Wnt Signaling Pathway Protein K29-linked Deubiquitination Phosphatidylinositol Phosphate Biosynthetic Process Protein K63-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Deubiquitination
Pathways			Degradation of beta-catenin by the destruction complex Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Male-pattern baldness ( 28196072)	Blood urea nitrogen levels ( 31152163) Creatine kinase levels ( 29403010) Height ( 25429064 31562340) Lung cancer ( 34062886)
Interacting Genes		10 interacting genes: CDR2L DAPP1 INCA1 LHX3 LMNA RSPH1 SPRY2 TRIM62 ZNF16 ZRANB1	130 interacting genes: AKT1 ARHGEF5 ARRDC2 ARRDC3 ATOSB BAHD1 BRD1 C1orf35 CARD9 CBX7 CBX8 CCDC120 CCDC13 CCDC185 CCDC187 CCHCR1 CCNL1 CDC45 CDK18 CDKL3 CNNM3 CORO7 CPNE7 CWF19L2 DCX DNAJB13 DTNB DUSP13B ENKD1 FAIM FAM124B FAM161A FAM161B FAM50B FAM90A1 FNDC11 GADD45GIP1 GAS2L2 GEM GLIS2 GPANK1 HOXB5 HOXC8 IL16 INO80B IP6K3 IQUB JRK KANK2 KIF9 KIFC3 LENG1 LMO3 LNX1 MAGEB4 MAGOH MCRS1 METTL21A MID2 MPPED1 MYEF2 NEK6 NUDT16L1 PHF1 PHF19 PKN1 PLEKHN1 PNMA5 POLDIP3 POLL PPP1R18 PSPC1 RAPGEF3 RASAL3 SCNM1 SDCBP SLC7A11 SNCA STAMBPL1 SUV39H1 SYT17 SYTL4 TBC1D3 TBC1D30 TBC1D3B TBC1D3C TBC1D3G TBC1D3K TCEANC THAP7 TIE1 TLE5 TNS4 TRAF3IP3 TRAF4 TRAF6 TRAPPC2 TRAPPC2B TSGA10IP TSPYL4 TSTD2 TTC23 TWIST1 UBASH3A UBC UBE2D1 UBE2G1 USP2 UVRAG VAV3 WT1 ZBTB24 ZBTB47 ZNF124 ZNF17 ZNF250 ZNF408 ZNF417 ZNF438 ZNF490 ZNF497 ZNF552 ZNF575 ZNF587 ZNF599 ZNF648 ZNF764 ZNF775 ZNF792 ZNF837
Entrez ID		55179	54764
HPRD ID		16874	11738
Ensembl ID		ENSG00000158234	ENSG00000019995
Uniprot IDs		Q9NVQ4	Q9UGI0
PDB IDs		2KW1 3MX7	3ZRH 5AF6
Enriched GO Terms of Interacting Partners?		Regulation Of Programmed Cell Death Organelle Localization Regulation Of Apoptotic Process Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity DNA Double-strand Break Attachment To Nuclear Envelope Cytoskeleton Organization Microtubule Cytoskeleton Organization Negative Regulation Of Programmed Cell Death Establishment Of Organelle Localization Negative Regulation Of Apoptotic Process Structural Constituent Of Nuclear Lamina Microtubule-based Process Cellular Response To Sodium Dodecyl Sulfate Regulation Of Phosphorylation Medial Motor Column Neuron Differentiation Ventral Spinal Cord Interneuron Specification Lung Development Prolactin Secreting Cell Differentiation Somatotropin Secreting Cell Differentiation Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Lung Growth Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Lens Fiber Cell Differentiation Golgi To Secretory Granule Transport Protein K29-linked Deubiquitination Positive Regulation Of Antifungal Innate Immune Response Radial Spoke Head 1 Radial Spoke Head 3 Lamin Filament Nuclear Pore Localization Ubiquitin-protein Transferase Inhibitor Activity Protein K33-linked Deubiquitination Radial Spoke Head	Protein Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Zinc Ion Binding Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Nuclear Speck Regulation Of Macromolecule Metabolic Process Microtubule Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process
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