CENPQ and AARD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CENPQ	AARD
Description		centromere protein Q	alanine and arginine rich domain containing protein
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol Actin Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Chromosome Segregation Metaphase Chromosome Alignment Positive Regulation Of Protein Localization To Kinetochore	Response To Testosterone
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		12 interacting genes: AARD ABI2 ABI3 APP BRME1 CENPU EMILIN1 HDAC7 KDM1A PLK1 SIKE1 SNX2	15 interacting genes: CENPQ CEP57 GRIPAP1 KIAA0753 KRT24 KRT27 LMO4 MAGEB4 NTAQ1 STX1A STX2 STX5 TFIP11 TSGA10 VPS37C
Entrez ID		55166	441376
HPRD ID		10788	18830
Ensembl ID		ENSG00000031691	ENSG00000205002
Uniprot IDs		Q7L2Z9	B2RU19 Q4LEZ3
PDB IDs		7PB8 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?		Cell Projection Morphogenesis SCAR Complex Actin-based Cell Projection Identical Protein Binding Insulin Receptor Binding Regulation Of Postsynapse Organization Dendritic Spine Neuron Maturation Cell Junction Organization Lamellipodium Regulation Of Lamellipodium Assembly Dendritic Shaft Regulation Of Dendritic Spine Morphogenesis Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Regulation Of Lamellipodium Organization Peptidyl-tyrosine Phosphorylation Regulation Of Plasma Membrane Bounded Cell Projection Organization Epigenetic Regulation Of Gene Expression Regulation Of Cell Projection Organization Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Synapse Organization Anatomical Structure Morphogenesis Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Signal Transduction Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Developmental Process Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Negative Regulation Of Cellular Component Organization Phosphorylation Synaptonemal Complex Disassembly Protein Phosphorylation Nuclear Division Golgi Inheritance Chromosome Regulation Of Double-strand Break Repair Via Homologous Recombination Signaling Adaptor Activity	SNARE Complex SNAP Receptor Activity SNARE Binding Vesicle Docking Calcium-dependent Protein Binding Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Organelle Membrane Fusion Vesicle Organization Organelle Fusion Presynaptic Active Zone Membrane Membrane Fusion Structural Molecule Activity Organelle Organization Organelle Localization Myosin Head/neck Binding Protein-N-terminal Glutamine Amidohydrolase Activity Extrinsic Component Of Postsynaptic Early Endosome Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Intracellular Protein Transport Structural Constituent Of Skin Epidermis Endomembrane System Protein Transport Spliceosomal Complex Disassembly Protein-N-terminal Asparagine Amidohydrolase Activity Positive Regulation Of Protein Localization To Kinetochore Negative Regulation Of Receptor Clustering Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Intermediate Filament Organization Membrane Organization Intracellular Protein Localization Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Ventral Spinal Cord Interneuron Differentiation U2-type Post-mRNA Release Spliceosomal Complex Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Establishment Of Protein Localization
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