CENPQ

Name	centromere protein Q
Structure
Interactors	12 interactors: AARD ABI2 ABI3 APP BRME1 CENPU EMILIN1 HDAC7 KDM1A PLK1 SIKE1 SNX2
GO Annotations	Cellular Component	Chromosome, Centromeric Region Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol Actin Cytoskeleton
	Molecular Function	Protein Binding
	Biological Process	Chromosome Segregation Metaphase Chromosome Alignment Positive Regulation Of Protein Localization To Kinetochore
Pathways	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
GWAS	Mean reticulocyte volume ( 32888494 ) Mean spheric corpuscular volume ( 32888494 )
Entrez ID	55166
HPRD ID	10788
Ensembl ID	ENSG00000031691
Uniprot IDs	Q7L2Z9
PDB IDs	7PB8 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH
GO Terms Enriched among Interactors ?	Cell Projection Morphogenesis SCAR Complex Actin-based Cell Projection Identical Protein Binding Insulin Receptor Binding Regulation Of Postsynapse Organization Dendritic Spine Neuron Maturation Cell Junction Organization Lamellipodium Regulation Of Lamellipodium Assembly Dendritic Shaft Regulation Of Dendritic Spine Morphogenesis Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Regulation Of Lamellipodium Organization Peptidyl-tyrosine Phosphorylation Regulation Of Plasma Membrane Bounded Cell Projection Organization Epigenetic Regulation Of Gene Expression Regulation Of Cell Projection Organization Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Synapse Organization Anatomical Structure Morphogenesis Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Signal Transduction Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Developmental Process Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Negative Regulation Of Cellular Component Organization Phosphorylation Synaptonemal Complex Disassembly Protein Phosphorylation Nuclear Division Golgi Inheritance Chromosome Regulation Of Double-strand Break Repair Via Homologous Recombination Signaling Adaptor Activity