FOSB and AGXT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FOSB	AGXT
Description		FosB proto-oncogene, AP-1 transcription factor subunit	alanine--glyoxylate aminotransferase
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol	Cytoplasm Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	L-serine-pyruvate Transaminase Activity Protein Binding Alanine-glyoxylate Transaminase Activity Transaminase Activity Amino Acid Binding Transferase Activity Pyridoxal Phosphate Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Response To Amphetamine Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Female Pregnancy Response To Xenobiotic Stimulus Response To Mechanical Stimulus Response To Progesterone Cellular Response To Hormone Stimulus Response To Nicotine Response To Cocaine Response To Morphine Response To Ethanol Positive Regulation Of Transcription By RNA Polymerase II Behavioral Response To Cocaine Response To Corticosterone Response To CAMP Cellular Response To Calcium Ion	L-serine Metabolic Process Notch Signaling Pathway Glyoxylate Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate L-cysteine Catabolic Process L-alanine Catabolic Process Glyoxylate Metabolic Process Oxalic Acid Secretion
Pathways		Estrogen-dependent gene expression NGF-stimulated transcription NGF-stimulated transcription Regulation of PD-L1(CD274) transcription	Glyoxylate metabolism and glycine degradation Peroxisomal protein import Peroxisomal protein import
Drugs			Pyridoxal phosphate Serine Glycine Alanine Aminooxyacetic acid N(6)-(pyridoxal phosphate)-L-lysine 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID
Diseases			Primary hyperoxaluria (HP)
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Heel bone mineral density ( 28869591 30598549)	Height ( 25282103 31562340) Urinary metabolites ( 26352407)
Interacting Genes		28 interacting genes: AGXT CENPO CREB5 CYTH4 DNMT3L ENKD1 EP300 FAM222B FAM90A1 FOXP3 GLIS2 JUNB JUND LINC00963 NCK2 NEDD9 NFE2L2 PHC2 PHF1 POGZ POU6F2 ROR2 SRA1 TENT5B TLE5 TLX3 VEZF1 ZC3H10	39 interacting genes: ACAT1 ACTMAP ATXN1L BATF3 CFAP68 CHIC2 CYSRT1 EFS FAM168B FHL5 FNTB FOSB GLP1R HOXA1 KRT31 KRT34 KRT37 KRT40 KRTAP1-1 KRTAP12-3 KRTAP3-1 KRTAP6-3 KRTAP8-1 KRTAP9-2 LPXN MDFI MORN5 NBPF19 NOTCH2NLA OIP5 PEX5 PLA2G10 PRDM6 PRICKLE4 RFX6 SNCAIP SPRYD7 TRAPPC14 TTC19
Entrez ID		2354	189
HPRD ID		01270	05048
Ensembl ID		ENSG00000125740	ENSG00000172482
Uniprot IDs		P53539	P21549
PDB IDs		5VPA 5VPB 5VPC 5VPD 5VPE 5VPF 6UCI 6UCL 6UCM 7UCC 7UCD	1H0C 1J04 2YOB 3R9A 4CBR 4CBS 4I8A 4KXK 4KYO 5F9S 5HHY 5LUC 5OFY 5OG0 6RV0 6RV1 7NS7
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of T-helper 17 Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Chromatin Regulation Of T-helper 17 Type Immune Response Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Factor AP-1 Complex Transcription Coregulator Binding Protein-DNA Complex DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Regulation Of T-helper Cell Differentiation DNA-binding Transcription Factor Activity Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Negative Regulation Of RNA Metabolic Process ESC/E(Z) Complex Sequence-specific Double-stranded DNA Binding Regulation Of CD4-positive, Alpha-beta T Cell Activation Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Activation CD4-positive, Alpha-beta T Cell Lineage Commitment Regulation Of Cell Differentiation Zinc Ion Binding Alpha-beta T Cell Lineage Commitment CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Alpha-beta T Cell Activation Negative Regulation Of Macromolecule Metabolic Process L-serine-pyruvate Transaminase Activity T Cell Lineage Commitment	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Intermediate Filament-based Process Negative Regulation Of B Cell Receptor Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?