TMEM45A and TRARG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM45A	TRARG1
Description		transmembrane protein 45A	trafficking regulator of GLUT4 (SLC2A4) 1 (gene/pseudogene)
Image			No pdb structure
GO Annotations	Cellular Component	Membrane	Cytoplasm Plasma Membrane Endomembrane System Membrane Cytoplasmic Vesicle Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding
	Biological Process		Cellular Response To Insulin Stimulus Glucose Import In Response To Insulin Stimulus Establishment Of Localization In Cell Protein Localization To Plasma Membrane Vesicle Fusion To Plasma Membrane Endosome To Plasma Membrane Protein Transport
Pathways
Drugs
Diseases
GWAS		Fasting glucose ( 34059833) Refractive error ( 32231278) Skin aging (microtopography measurement) ( 28502801)
Interacting Genes		9 interacting genes: APOA2 ARLN ERMP1 GJA8 IGFBP5 PLN SSMEM1 TMEM19 TRARG1	102 interacting genes: APH1A APH1B AQP12B AQP2 ARL13B BCL2L13 BIK BSCL2 C6orf89 CARINH CCR4 CD300E CD53 CD79A CLDN12 CLDN7 CLDN8 CLEC10A CXCR1 CXCR2 DAGLA EBP EFNA4 ELOVL4 ERGIC3 FAM209A FNDC9 FUT3 GJB3 GPR151 GPR42 GPR61 GPRC5D HSF2BP IFNGR2 IL3RA KASH5 KCNC1 KRT34 KRTAP5-9 LAPTM4B LHFPL5 LY6E MEOX2 MFF MRM1 MRPS18B MTIF3 NPFFR2 NPY2R ODF4 OPN1LW OPRM1 OR7D4 OSTC PDZK1IP1 PLEKHB2 PSCA RHBDL1 RHCG RTP4 SCN3B SDCBP SLC10A1 SLC10A6 SLC13A4 SLC14A2 SLC16A2 SLC1A5 SLC30A2 SLC34A2 SLC35F1 SLC36A1 SLC38A1 SLC38A11 SLC38A6 SLC39A1 SLC71A2 SLC7A1 SLC7A14 SLCO3A1 SPAG4 SSMEM1 SYNPR TAAR9 TM4SF18 TMC4 TMEM179B TMEM237 TMEM248 TMEM31 TMEM45A TMEM52B TMEM69 TMEM71 TMEM80 TMEM9 TMPPE TTYH2 WFS1 YIPF6 ZDHHC4
Entrez ID		55076	286753
HPRD ID		07647	18248
Ensembl ID		ENSG00000181458	ENSG00000184811
Uniprot IDs		J3KQ06 Q9NWC5	Q8IXB3
PDB IDs		7OQZ
Enriched GO Terms of Interacting Partners?		Regulation Of System Process Negative Regulation Of Muscle Hypertrophy Response To Peptide Hormone Regulation Of Muscle System Process Negative Regulation Of Skeletal Muscle Hypertrophy Response To Hormone Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Regulation Of The Force Of Heart Contraction By Cardiac Conduction Calcium Ion-transporting ATPase Complex Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Peptidyl-methionine Modification High-density Lipoprotein Particle Receptor Binding Negative Regulation Of Cholesterol Import Insulin-like Growth Factor Binding Protein Complex Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Receptor Ligand Activity Phosphatidylcholine-sterol O-acyltransferase Activator Activity Regulation Of Intestinal Cholesterol Absorption Protein Oxidation Diacylglycerol Catabolic Process Regulation Of Cholesterol Import Lipase Inhibitor Activity Apolipoprotein Receptor Binding Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Clearance Gap Junction-mediated Intercellular Transport Mammary Gland Involution Insulin-like Growth Factor Ternary Complex Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Transporter Inhibitor Activity Regulation Of Cardiac Muscle Cell Membrane Potential Circadian Sleep/wake Cycle Process ATPase Inhibitor Activity Regulation Of Relaxation Of Cardiac Muscle Sleep Response To Insulin Response To Thyroxine TOM Complex Mitochondrion Targeting Sequence Binding Response To L-phenylalanine Derivative Glucose Import In Response To Insulin Stimulus	Membrane Plasma Membrane Transmembrane Transport Amino Acid Transmembrane Transport Protein Binding Amino Acid Transmembrane Transporter Activity Amino Acid Transport Carboxylic Acid Transport Organic Acid Transport L-amino Acid Transport G Protein-coupled Receptor Activity Carboxylic Acid Transmembrane Transport Organic Acid Transmembrane Transport Organic Anion Transport L-alpha-amino Acid Transmembrane Transport Symporter Activity Amino Acid Import Across Plasma Membrane L-glutamine Transmembrane Transporter Activity Glutamine Transport Interleukin-8-mediated Signaling Pathway Interleukin-8 Receptor Activity Apical Plasma Membrane Monoatomic Ion Transport Basolateral Plasma Membrane Interleukin-8 Binding Sodium Ion Transport Transport Across Blood-brain Barrier Neutral L-amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity L-glutamine Import Across Plasma Membrane Bile Acid:sodium Symporter Activity Transmembrane Transporter Activity Gamma-secretase Complex G Protein-coupled Receptor Signaling Pathway Metal Ion Transport Inorganic Ion Transmembrane Transport C-X-C Chemokine Receptor Activity Notch Receptor Processing
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