ZWILCH and ZW10

Number of citations of the paper that reports this interaction (PMID 12686595)
32

Data Source:
HPRD (in vitro, in vivo)

		ZWILCH	ZW10
Gene Name		zwilch kinetochore protein	zw10 kinetochore protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Cytosol	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Kinetochore Microtubule Cytosol Membrane
	Molecular Function	Protein Binding	Protein Binding Centromeric DNA Binding
	Biological Process	Mitotic Cell Cycle Mitotic Nuclear Division Mitotic Cell Cycle Checkpoint Cell Division	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Protein Complex Assembly ER To Golgi Vesicle-mediated Transport Golgi Organization Mitotic Metaphase Plate Congression Mitotic Cell Cycle Checkpoint Regulation Of Exit From Mitosis Meiotic Nuclear Division Protein Transport Protein Localization To Kinetochore Cell Division
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: KNTC1 ZW10	7 interactors: APP DCTN2 PTF1A RINT1 UBC ZWILCH ZWINT
Entrez ID		55055	9183
HPRD ID		07640	04902
Ensembl ID		ENSG00000174442	ENSG00000086827
Uniprot IDs		Q9H900	A1A528 O43264
PDB IDs		3IF8
Enriched GO Terms of Interacting Partners?		Regulation Of Exit From Mitosis Regulation Of Mitotic Nuclear Division Mitotic Cell Cycle Checkpoint Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Regulation Of Cell Division Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Cell Division Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Process Protein Localization To Kinetochore Mitotic Cell Cycle Process Protein Localization To Chromosome, Centromeric Region Mitotic Cell Cycle Regulation Of Organelle Organization Regulation Of Cell Cycle Protein Complex Assembly Cell Cycle Process Mitotic Metaphase Plate Congression Protein Localization To Chromosome Metaphase Plate Congression Cell Cycle Establishment Of Mitotic Spindle Orientation Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Chromosome Localization Spindle Localization Cellular Component Assembly Mitotic Sister Chromatid Segregation Golgi Organization Regulation Of Cellular Component Organization Sister Chromatid Segregation ER To Golgi Vesicle-mediated Transport Establishment Of Cell Polarity Meiotic Nuclear Division Establishment Or Maintenance Of Cell Polarity Meiotic Cell Cycle Organelle Organization Chromosome Segregation Golgi Vesicle Transport Establishment Of Organelle Localization Organelle Localization Endomembrane System Organization Microtubule Cytoskeleton Organization	Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Mitotic Cell Cycle Checkpoint Cell Cycle Intracellular Receptor Signaling Pathway Mitotic Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Mitotic Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Mitotic Nuclear Division Establishment Of Localization In Cell Cell Cycle Process Cellular Localization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Cell Cycle Regulation Of ERBB Signaling Pathway Regulation Of Cell Cycle Process Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint G2/M Transition Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Notch Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Neural Retina Development Collateral Sprouting Axon Midline Choice Point Recognition Amacrine Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Axon Choice Point Recognition Antigen Processing And Presentation Of Peptide Antigen Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Phase Transition Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Phase Transition Neuron Remodeling Exocrine Pancreas Development Positive Regulation Of Cell Cycle Antigen Processing And Presentation Positive Regulation Of Proteolysis Viral Protein Processing Regulation Of DNA Damage Checkpoint Regulation Of ER To Golgi Vesicle-mediated Transport
Tagcloud ?		associate attachments attain aurora cenp centromere checkpoint depleted dictates dissociation dynein generate kinetochore kinetochores loading mad1 maintains mature microtubule microtubules prometaphase rod rzz spindle stripping switch tightly uncovered zw10	apparatus autophagy checkpoint comprises counterpart cytokinesis decay discuss dsl1 dsl3 endoplasmic endosome golgi intercorrelation metazoan moonlighting nag nrz participate reticulum retrograde rint1 sec39 summarize tethering tip20 trafficking transport vesicle
Tagcloud (Difference) ?		associate attachments attain aurora cenp centromere depleted dictates dissociation dynein generate kinetochore kinetochores loading mad1 maintains mature microtubule microtubules prometaphase rod rzz spindle stripping switch tightly uncovered	apparatus autophagy comprises counterpart cytokinesis decay discuss dsl1 dsl3 endoplasmic endosome golgi intercorrelation metazoan moonlighting nag nrz participate reticulum retrograde rint1 sec39 summarize tethering tip20 trafficking transport vesicle
Tagcloud (Intersection) ?		checkpoint zw10