ZWILCH

Description		zwilch kinetochore protein
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Chromosome Kinetochore Microtubule Cytosol RZZ Complex
	Molecular Function	Protein Binding
	Biological Process	Mitotic Spindle Assembly Checkpoint Signaling Protein Localization To Kinetochore Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body mass index ( 29273807)
Interacting Genes		3 interacting genes: KNTC1 UBC ZW10
Entrez ID		55055
HPRD ID		07640
Ensembl ID		ENSG00000174442
Uniprot IDs		A8K4T3 Q9H900
PDB IDs		3IF8 7QPG
Enriched GO Terms of Interacting Partners?		RZZ Complex Protein Localization To Kinetochore Regulation Of Exit From Mitosis Regulation Of Attachment Of Spindle Microtubules To Kinetochore Mitotic Spindle Assembly Checkpoint Signaling Mitotic Sister Chromatid Segregation Negative Regulation Of Mitotic Metaphase/anaphase Transition Kinetochore Microtubule Negative Regulation Of Mitotic Nuclear Division Protein Localization To Chromosome, Centromeric Region Sister Chromatid Segregation Nuclear Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Regulation Of Chromosome Separation Negative Regulation Of Chromosome Organization Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Sister Chromatid Segregation Protein Localization To Chromosome Regulation Of Mitotic Nuclear Division Regulation Of Chromosome Segregation Protein Localization To Kinetochore Involved In Kinetochore Assembly Chromosome Segregation Regulation Of Nuclear Division Spindle Pole Chromosome, Centromeric Region Negative Regulation Of Mitotic Cell Cycle Phase Transition Kinetochore Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Dsl1/NZR Complex Spindle Regulation Of Chromosome Organization Negative Regulation Of Cell Cycle Process Centromeric DNA Binding Regulation Of Mitotic Cell Cycle Phase Transition Chromosome Organization Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Division Protein Tag Activity Regulation Of Mitotic Cell Cycle Protein Localization To Organelle Chromosome Negative Regulation Of Cellular Component Organization Regulation Of Cell Cycle Process Establishment Of Mitotic Spindle Orientation Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Mitotic Metaphase Chromosome Alignment Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
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